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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL11 Antibody Picoband®

SKU : BHA21001326

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Mfr.No.	A01160-1, A01160-1-10ug, A01160-1-Biotin, A01160-1-Cy3, A01160-1-Dylight488, A01160-1-Dylight550, A01160-1-Dylight594, A01160-1-FITC, A01160-1-HRP, A01160-1-APC, A01160-1-PE, A01160-1-iFluor647, A01160-1-carrier-free
Alternative Names	interleukin 11
Background	Interleukin 11 (IL-11) is a protein that in humans is encoded by the IL11 gene. The protein encoded by this gene is a member of the gp130 family of cytokines. This gene is mapped to 19q13.42. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. What's more, IL-11 can stimulate the growth of certain lymphocytes and it has functions in many other tissues, including the brain, gut, testis and bone. In transgenic mice, overexpression of the human IL11 gene resulted in the stimulation of bone formation to increase cortical thickness and strength of long bones.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IL11 Antibody Picoband® catalog # A01160-1. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver
Host	Rabbit
Immunogen Region	E. coli-derived rat IL11 recombinant protein (Position: P25-L199).
Isotype	Rabbit IgG
Molecular Weight	21 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-11; IL-11; Il11;
Tissue Specificity	Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Il11: Q99MF5
Gene Id	171040
Gene Name	Il11
Subcellular Location	Secreted

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Chen, Q., Rabach, L., Noble, P., Zheng, T., Lee, C. G., Homer, R. J., Elias, J. A. IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling. J. Immun. 174: 2305-2313, 2005.<br /><br />2. McKinley, D., Wu, Q., Yang-Feng, T., Yang, Y.-C. Genomic sequence and chromosomal location of human interleukin-11 gene (IL11). Genomics 13: 814-819, 1992.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001326-1	A01160-1	100 ug	-	$370		Add to Cart
BHA21001326-2	A01160-1-10ug	10 ug	Sample	$99		Add to Cart
BHA21001326-3	A01160-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001326-4	A01160-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001326-5	A01160-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001326-6	A01160-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001326-7	A01160-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001326-8	A01160-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21001326-9	A01160-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21001326-10	A01160-1-APC	100 ug	APC	$670		Add to Cart
BHA21001326-11	A01160-1-PE	100 ug	PE	$670		Add to Cart
BHA21001326-12	A01160-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001326-13	A01160-1-carrier-free	100 ug	carrier-free	$370		Add to Cart

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