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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IKK gamma/IKBKG Antibody Picoband®

SKU : BHA21006881

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Mfr.No.	PA1551, PA1551-10ug, PA1551-Biotin, PA1551-Cy3, PA1551-Dylight488, PA1551-Dylight550, PA1551-Dylight594, PA1551-FITC, PA1551-HRP, PA1551-APC, PA1551-PE, PA1551-iFluor647, PA1551-carrier-free
Alternative Names	NF-kappa-B essential modulator
Background	NF-kappa-B essential modulator (NEMO), also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-gamma), is a protein that in humans is encoded by the IKBKG gene. This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IKK gamma/IKBKG Antibody catalog # PA1551. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems t
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of mouse IKK gamma, different from the relative rat sequence by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	68 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	NF-kappa-B essential modulator;NEMO;IkB kinase-associated protein 1;IKKAP1;mFIP-3;Inhibitor of nuclear factor kappa-B kinase subunit gamma;I-kappa-B kinase subunit gamma;IKK-gamma;IKKG;IkB kinase subunit gamma;NF-kappa-B essential modifier;Ikbkg;Nemo;
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Uniprot	O88522
Gene Name	IKBKG
Sequence	Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.
Subcellular Location	Cytoplasm . Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Rothwarf, D. M., Zandi, E., Natoli, G., Karin, M.IKK-gamma is an essential regulatory subunit of the I-kappa-B kinase complex.Nature 395: 297-300, 1998. <br /><br />2. Yamaoka, S., Courtois, G., Bessia, C., Whiteside, S. T., Weil, R., Agou, F., Kirk, H. E., Kay, R. J., Israel, A.Complementation cloning of NEMO, a component of the I-kappa-B kinase complex essential for NF-kappa-B activation.Cell 93: 1231-1240, 1998.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006881-1	PA1551	-	100 ug	$370		Add to Cart
BHA21006881-2	PA1551-10ug	Sample	10 ug	$99		Add to Cart
BHA21006881-3	PA1551-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006881-4	PA1551-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006881-5	PA1551-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006881-6	PA1551-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006881-7	PA1551-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006881-8	PA1551-FITC	FITC	100 ug	$570		Add to Cart
BHA21006881-9	PA1551-HRP	HRP	100 ug	$570		Add to Cart
BHA21006881-10	PA1551-APC	APC	100 ug	$670		Add to Cart
BHA21006881-11	PA1551-PE	PE	100 ug	$670		Add to Cart
BHA21006881-12	PA1551-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006881-13	PA1551-carrier-free	carrier-free	100 ug	$370		Add to Cart

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