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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IGFBP1 Antibody Picoband®

SKU : BHA21001193

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Mfr.No.	A00922, A00922-10ug, A00922-Biotin, A00922-Cy3, A00922-Dylight488, A00922-Dylight550, A00922-Dylight594, A00922-FITC, A00922-HRP, A00922-APC, A00922-PE, A00922-iFluor647, A00922-carrier-free
Alternative Names	Insulin-like growth factor-binding protein 1
Background	IGFBP1, Insulin-like growth factor-binding protein 1, also known as placental protein 12 (PP12), is a protein that in humans is encoded by the IGFBP1 gene. The IGFBP1 gene has 4 exons and spans 5.9 kb. And the IGFBP1 gene is localized to 7p13-p12 by in situ hybridization. This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alteate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IGFBP1 Antibody Picoband® catalog # A00922. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migrati
Host	Rabbit
Immunogen Region	E.coli-derived human IGFBP1 recombinant protein (Position: A69-N259). Human IGFBP1 shares 67.8% and 69.3% amino acid (aa) sequence identity with mouse and rat IGFBP1, respectively.
Isotype	Rabbit IgG
Molecular Weight	30 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Insulin-like growth factor-binding protein 1;IBP-1;IGF-binding protein 1;IGFBP-1;Placental protein 12;PP12;IGFBP1;IBP1;
Tissue Specificity	High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P08833
Gene Id	3484
Gene Name	IGFBP1
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, By Heat <br>

Reference	1. Alitalo, T., Kontula, K., Koistinen, R., Aalto-Setala, K., Julkunen, M., Janne, O. A., Seppala, M., de la Chapelle, A.The gene encoding human low-molecular weight insulin-like growth-factor binding protein (IGF-BP25): regional localization to 7p12-p13 and description of a DNA polymorphism.Hum. Genet. 83: 335-338, 1989.<br /><br />2. Brinkman, A., Groffen, C. A. H., Kortleve, D. J., Drop, S. L. S.Organization of the gene encoding the insulin-like growth factor binding protein IBP-1.Biochem. Biophys. Res. Commun. 157: 898-907, 1988.<br /><br />3. Leu, J. I.-J., George, D. L.Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria.Genes Dev. 21: 3095-3109, 2007.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001193-1	A00922	100 ug	-	$370		Add to Cart
BHA21001193-2	A00922-10ug	10 ug	Sample	$99		Add to Cart
BHA21001193-3	A00922-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001193-4	A00922-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001193-5	A00922-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001193-6	A00922-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001193-7	A00922-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001193-8	A00922-FITC	100 ug	FITC	$570		Add to Cart
BHA21001193-9	A00922-HRP	100 ug	HRP	$570		Add to Cart
BHA21001193-10	A00922-APC	100 ug	APC	$670		Add to Cart
BHA21001193-11	A00922-PE	100 ug	PE	$670		Add to Cart
BHA21001193-12	A00922-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001193-13	A00922-carrier-free	100 ug	carrier-free	$370		Add to Cart

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