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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IGF1 Antibody

SKU : BHA21002972

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Mfr.No.	A00148, A00148-10ug, A00148-Biotin, A00148-Cy3, A00148-Dylight488, A00148-Dylight550, A00148-Dylight594, A00148-FITC, A00148-HRP, A00148-APC, A00148-PE, A00148-iFluor647, A00148-carrier-free
Alternative Names	Angiogenin
Background	Insulin-like growth factor 1 (IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al. (1990) placed the mouse IGF1 gene on chromosome 10.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio <a href="https://www.bosterbio.com/anti-igf-1-antibody-pa1374-boster.html" style="color:#EA8D28">Anti-IGF1 Antibody</a> Picoband® catalog # A00148. Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human.
Function	Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodo
Host	Rabbit
Immunogen Region	E.coli-derived human IGF1 recombinant protein (Position: P50-A118).
Isotype	Rabbit IgG
Molecular Weight	25 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Angiogenin;3.1.27.-;Ribonuclease 5;RNase 5;ANG;RNASE5;
Tissue Specificity	Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P05019
Gene Id	3479
Gene Name	IGF1
Subcellular Location	Nucleus . Secreted, extracellular space, extracellular matrix, basement membrane. Nucleus, nucleolus. Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IHC
Description	Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA (Cap), 1-5ug/ml, Human<br>

Reference	1. Höppener JW, de Pagter-Holthuizen P, Geurts van Kessel AH, Jansen M, Kittur SD, Antonarakis SE, Lips CJ, Sussenbach JS (1985). "The human gene encoding insulin-like growth factor I is located on chromosome 12". Hum. Genet. 69 (2): 15760.<br /><br />2. Jansen M, van Schaik FM, Ricker AT, Bullock B, Woods DE, Gabbay KH, Nussbaum AL,Sussenbach JS, Van den Brande JL (1983). "Sequence of cDNA encoding human insulin-like growth factor I precursor". Nature 306 (5943): 60911.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002972-1	A00148	-	100 ug	$370		Add to Cart
BHA21002972-2	A00148-10ug	Sample	10 ug	$99		Add to Cart
BHA21002972-3	A00148-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002972-4	A00148-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002972-5	A00148-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002972-6	A00148-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002972-7	A00148-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002972-8	A00148-FITC	FITC	100 ug	$570		Add to Cart
BHA21002972-9	A00148-HRP	HRP	100 ug	$570		Add to Cart
BHA21002972-10	A00148-APC	APC	100 ug	$670		Add to Cart
BHA21002972-11	A00148-PE	PE	100 ug	$670		Add to Cart
BHA21002972-12	A00148-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002972-13	A00148-carrier-free	carrier-free	100 ug	$370		Add to Cart

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