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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IFITM1 Antibody Picoband®

SKU : BHA21006663

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Mfr.No.	PA1112, PA1112-10ug, PA1112-Biotin, PA1112-Cy3, PA1112-Dylight488, PA1112-Dylight550, PA1112-Dylight594, PA1112-FITC, PA1112-HRP, PA1112-APC, PA1112-PE, PA1112-iFluor647, PA1112-carrier-free
Alternative Names	Interferon-induced transmembrane protein 1
Background	Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their patte of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17-kDa proteins to inhibit cell growth.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IFITM1 Antibody catalog # PA1112. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influen
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human IFITM1.
Isotype	Rabbit IgG
Molecular Weight	70-74 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interferon-induced transmembrane protein 1;Dispanin subfamily A member 2a;DSPA2a;Interferon-induced protein 17;Interferon-inducible protein 9-27;Leu-13 antigen;CD225;IFITM1;CD225, IFI17;
Tissue Specificity	Bone (at protein level). Levels greatly elevated in colon cancer, cervical cancer, esophageal cancer and ovarian cancer. Expressed in glioma cell lines. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P13164
Gene Name	IFITM1
Sequence	Belongs to the intermediate filament family.
Subcellular Location	Cell membrane ; Single-pass membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Human, -<br>Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Tanaka, S. S.; Yamaguchi, Y. L.; Tsoi, B.; Lickert, H.; Tam, P. P. L. : IFITM/Mil/Fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion. Dev. Cell 9: 745-756, 2005.<br /><br />2. Deblandre, G. A.; Marinx, O. P.; Evans. S. S.; Majjaj, S.; Leo, O.; Caput, D.; Huez, G. A.; Wathelet, M. G. : Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth. J. Biol. Chem. 270: 23860-23866, 1995.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006663-1	PA1112	-	100 ug	$370		Add to Cart
BHA21006663-2	PA1112-10ug	Sample	10 ug	$99		Add to Cart
BHA21006663-3	PA1112-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006663-4	PA1112-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006663-5	PA1112-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006663-6	PA1112-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006663-7	PA1112-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006663-8	PA1112-FITC	FITC	100 ug	$570		Add to Cart
BHA21006663-9	PA1112-HRP	HRP	100 ug	$570		Add to Cart
BHA21006663-10	PA1112-APC	APC	100 ug	$670		Add to Cart
BHA21006663-11	PA1112-PE	PE	100 ug	$670		Add to Cart
BHA21006663-12	PA1112-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006663-13	PA1112-carrier-free	carrier-free	100 ug	$370		Add to Cart

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