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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IDO-2/IDO2 Antibody Picoband®

SKU : BHA21003252

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Mfr.No.	A06002-2, A06002-2-10ug, A06002-2-Biotin, A06002-2-Cy3, A06002-2-Dylight488, A06002-2-Dylight550, A06002-2-Dylight594, A06002-2-FITC, A06002-2-HRP, A06002-2-APC, A06002-2-PE, A06002-2-iFluor647, A06002-2-carrier-free
Alternative Names	solute carrier family 25 member 1
Background	IDO2 (Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan (D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IDO-2/IDO2 Antibody Picoband® catalog # A06002-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Impo
Host	Rabbit
Immunogen Region	E.coli-derived human IDO-2/IDO2 recombinant protein (Position: M1-R357).
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse, Rat, Monkey
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Tricarboxylate transport protein, mitochondrial; Citrate transport protein; CTP; Solute carrier family 25 member 1; Tricarboxylate carrier protein; SLC25A1; SLC20A3
Tissue Specificity	Detected in brain. Detected at very much lower levels in heart, lung, placenta and skeletal muscle. Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q6ZQW0
Gene Id	16935
Gene Name	IDO2
Subcellular Location	Mitochondrion inner membrane. Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Mouse, Rat, Monkey<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Ball, H. J., Sanchez-Perez, A., Weiser, S., Austin, C. J. D., Astelbauer, F., Miu, J., McQuillan, J. A., Stocker, R., Jermin, L. S., Hunt, N. H. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice. Gene 396: 203-213, 2007.<br /><br />2. Metz, R., DuHadaway, J. B., Kamasani, U., Laury-Kleintop, L., Muller, A. J., Prendergast, G. C. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res. 67: 7082-7087, 2007.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003252-1	A06002-2	-	100 ug	$370		Add to Cart
BHA21003252-2	A06002-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003252-3	A06002-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003252-4	A06002-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003252-5	A06002-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003252-6	A06002-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003252-7	A06002-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003252-8	A06002-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003252-9	A06002-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003252-10	A06002-2-APC	APC	100 ug	$670		Add to Cart
BHA21003252-11	A06002-2-PE	PE	100 ug	$670		Add to Cart
BHA21003252-12	A06002-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003252-13	A06002-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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