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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IDH3G Antibody Picoband®

SKU : BHA21005711

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Mfr.No.	A10370-3, A10370-3-10ug, A10370-3-Biotin, A10370-3-Cy3, A10370-3-Dylight488, A10370-3-Dylight550, A10370-3-Dylight594, A10370-3-FITC, A10370-3-HRP, A10370-3-APC, A10370-3-PE, A10370-3-iFluor647, A10370-3-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Isocitrate dehydrogenase (NAD) subunit gamma, mitochondrial is an enzyme that in humans is encoded by the IDH3G gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alteatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-IDH3G Antibody Picoband® catalog # A10370-3. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human PAIP1 recombinant protein (Position: R92-Q420). Human PAIP1 shares 97.6% amino acid (aa) sequence identity with mouse PAIP1.
Isotype	IgG
Molecular Weight	40 kDa
Reactivity	Human, Mouse, Rat, Monkey
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P51553
Gene Id	3421
Gene Name	IDH3G
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Monkey, Mouse, Rat<br> Immunohistochemistry, 2-5 ug/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Brenner, V., Nyakatura, G., Rosenthal, A., Platzer, M. Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH-gamma and TRAP-delta is conserved in rat and mouse. Genomics 44: 8-14, 1997.<br /><br />2. Fink, J. M., Dobyns, W. B., Guerrini, R., Hirsch, B. A. Identification of a duplication of Xq28 associated with bilateral periventricular nodular heterotopia. Am. J. Hum. Genet. 61: 379-387, 1997. <br /><br />3. Fox, J. W., Lamperti, E. D., Eksioglu, Y. Z., Hong, S. E., Feng, Y., Graham, D. A., Scheffer, I. E., Dobyns, W. B., Hirsch, B. A., Radtke, R. A., Berkovic, S. F., Huttenlocher, P. R., Walsh, C. A. Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia. Neuron 21: 1315-1325, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005711-1	A10370-3	-	100 ug	$370		Add to Cart
BHA21005711-2	A10370-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21005711-3	A10370-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005711-4	A10370-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005711-5	A10370-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005711-6	A10370-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005711-7	A10370-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005711-8	A10370-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21005711-9	A10370-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21005711-10	A10370-3-APC	APC	100 ug	$670		Add to Cart
BHA21005711-11	A10370-3-PE	PE	100 ug	$670		Add to Cart
BHA21005711-12	A10370-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005711-13	A10370-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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