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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Human NFAT4 DyLight® 488 conjugated NFATC3 Antibody

SKU : BHA21001874

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Mfr.No.	A02727-Dyl488
Alternative Names	nuclear factor of activated T-cells 3
Background	Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene. The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Human NFAT4 DyLight® 488 conjugated NFATC3 Antibody catalog # A02727-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Function	Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2.
Host	Rabbit
Immunogen Region	E. coli-derived human NFAT4 recombinant protein (Position: K630-L712).
Isotype	Rabbit IgG
Molecular Weight	39 kDa
Reactivity	Human
Specificity	No cross reactivity with other proteins.
Synonyms	Nuclear factor of activated T-cells, cytoplasmic 3; NF-ATc3; NFATc3; NFATx; T-cell transcription factor NFAT4; NF-AT4; NFATC3; NFAT4
Tissue Specificity	Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, heart, placenta and pancreas. Isoform 3 is expressed in thymus and kidney. Isoform 4 is expressed in thymus and skeletal muscle.
Note	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Uniprot	Q12968
Gene Id	4775
Gene Name	NFATC3
Subcellular Location	Cytoplasm.

Conjugates	DyLight 488

Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form	Liquid
Storage	At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications	Flow Cytometry
Description	Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells

Reference	1. Hoey T, Sun YL, Williamson K, Xu X (May 1995). "Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins". Immunity. 2 (5): 46172.<br /><br />2. Horsley, V., Pavlath, G. K. NFAT: ubiquitous regulator of cell differentiation and adaptation. J. Cell Biol. 156: 771-774, 2002.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001874-1	A02727-Dyl488	100 ug	-	$515		Add to Cart

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