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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Human BMP5 DyLight® 488 conjugated Antibody

SKU : BHA21001802

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Mfr.No.	A05887-Dyl488
Alternative Names	bone morphogenetic protein 5
Background	Bone morphogenetic protein 5 is a protein that in humans is encoded by the BMP5 gene. This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. And this protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Human BMP5 DyLight® 488 conjugated Antibody catalog # A05887-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Function	Induces cartilage and bone formation.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human BMP5, different from the related mouse sequence by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	39 kDa
Reactivity	Human
Specificity	No cross reactivity with other proteins.
Synonyms	Bone morphogenetic protein 5; BMP-5; BMP5
Tissue Specificity	Expressed in the lung and liver.
Note	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Uniprot	P22003
Gene Id	653
Gene Name	BMP5
Subcellular Location	Secreted.

Conjugates	DyLight 488

Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form	Liquid
Storage	At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications	Flow Cytometry
Description	Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells

Reference	1. "Entrez Gene: BMP5 bone morphogenetic protein 5".<br /><br />2. Beck HN, Drahushuk K, Jacoby DB, Higgins D, Lein PJ (Mar 2003). "Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons". BMC Neurosci 2: 12.<br /><br />3. Hahn GV, Cohen RB, Wozney JM, Levitz CL, Shore EM, Zasloff MA, Kaplan FS (Dec 1992). "A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7". Genomics 14 (3): 75962.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001802-1	A05887-Dyl488	100 ug	-	$515		Add to Cart

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