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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Human ACTN3 DyLight® 550 conjugated Antibody

SKU : BHA21001976

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Mfr.No.	A02693-Dyl550
Alternative Names	actinin alpha 3 (gene/pseudogene)
Background	Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Human ACTN3 DyLight® 550 conjugated Antibody catalog # A02693-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
Function	F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human ACTN3, different from the related mouse sequence by five amino acids.
Isotype	Rabbit IgG
Molecular Weight	39 kDa
Reactivity	Human
Specificity	No cross reactivity with other proteins.
Synonyms	Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein; ACTN3
Tissue Specificity	Expressed only in a subset of type 2 skeletal muscle fibers.
Note	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Uniprot	Q08043
Gene Id	89
Gene Name	ACTN3

Conjugates	DyLight 550

Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form	Liquid
Storage	At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications	Flow Cytometry
Description	Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells

Reference	1. Papadimitriou ID, Papadopoulos C, Kouvatsi A, Triantaphyllidis C (April 2008). "The ACTN3 gene in elite Greek track and field athletes". Int J Sports Med 29 (4): 3525.<br /><br />2. Yang N, MacArthur DG, Gulbin JP, Hahn AG, Beggs AH, Easteal S, North K (September 2003). "ACTN3 genotype is associated with human elite athletic performance". Am. J. Hum. Genet. 73 (3): 62731.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001976-1	A02693-Dyl550	100 ug	-	$515		Add to Cart

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