JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-HSD17B6 Antibody Picoband®

SKU : BHA21006763

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PA1386, PA1386-10ug, PA1386-Biotin, PA1386-Cy3, PA1386-Dylight488, PA1386-Dylight550, PA1386-Dylight594, PA1386-FITC, PA1386-HRP, PA1386-APC, PA1386-PE, PA1386-iFluor647, PA1386-carrier-free
Alternative Names	17-beta-hydroxysteroid dehydrogenase type 6
Background	Hydroxysteroid 17-beta dehydrogenase 6 is an enzyme that in humans is encoded by the HSD17B6 gene. The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. Baker ME et al point out expression of 17beta-HSDs had an important role in the early evolution of the physiological response to androgens and estrogens. Biswas and Russell concluded that 17beta-HSD6 and RoDH play opposing roles in androgen action; 17beta-HSD6 inactivates 3alpha-adiol by conversion to androsterone and RoDH activates 3alpha-adiol by conversion to dihydrotestosterone. The synthesis of an active steroid hormone by back conversion of an inactive metabolite represents a potentially important mechanism by which the steady state level of a transcriptional effector can be regulated.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-HSD17B6 Antibody catalog # PA1386. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3- alpha,17-beta-d
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human HSD17B6.
Isotype	Rabbit IgG
Molecular Weight	35 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	17-beta-hydroxysteroid dehydrogenase type 6;17-beta-HSD 6;17-beta-HSD6;1.1.1.105;1.1.1.239;1.1.1.62;3-alpha->beta-hydroxysteroid epimerase;3-alpha->beta-HSE;Oxidative 3-alpha hydroxysteroid dehydrogenase;Short chain dehydrogenase/reductase family 9C member 6;HSD17B6;RODH, SDR9C6;
Tissue Specificity	Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	O14756
Gene Name	HSD17B6
Sequence	Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Subcellular Location	Microsome membrane ; Peripheral membrane protein ; Lumenal side . Early endosome membrane ; Peripheral membrane protein ; Lumenal side .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat <br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Baker ME (Feb 2001). "Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action". Mol Cell Endocrinol 171 (1-2): 2115. doi:10.1016/S0303-7207(00)00414-7. PMID 11165032.<br /><br />2. Biswas, M. G., Russell, D. W. Expression cloning and characterization of oxidative 17-beta- and 3-alpha hydroxysteroid dehydrogenases from rat and human prostate. J. Biol. Chem. 272: 15959-15966, 1997.<br /><br />

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006763-1	PA1386	-	100 ug	$370		Add to Cart
BHA21006763-2	PA1386-10ug	Sample	10 ug	$99		Add to Cart
BHA21006763-3	PA1386-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006763-4	PA1386-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006763-5	PA1386-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006763-6	PA1386-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006763-7	PA1386-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006763-8	PA1386-FITC	FITC	100 ug	$570		Add to Cart
BHA21006763-9	PA1386-HRP	HRP	100 ug	$570		Add to Cart
BHA21006763-10	PA1386-APC	APC	100 ug	$670		Add to Cart
BHA21006763-11	PA1386-PE	PE	100 ug	$670		Add to Cart
BHA21006763-12	PA1386-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006763-13	PA1386-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.