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Home / Primary Antibodies / Polyclonal Antibodies

Anti-HRPT2/CDC73 Antibody Picoband®

SKU : BHA21000428

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Mfr.No.	PB9532, PB9532-10ug, PB9532-Biotin, PB9532-Cy3, PB9532-Dylight488, PB9532-Dylight550, PB9532-Dylight594, PB9532-FITC, PB9532-HRP, PB9532-APC, PB9532-PE, PB9532-iFluor647, PB9532-carrier-free
Alternative Names	Parafibromin
Background	Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-HRPT2/CDC73 Antibody Picoband® catalog # PB9532. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression. Component of the PAF1 complex (PAF1C) which has multiple funct
Host	Rabbit
Immunogen Region	E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.
Isotype	Rabbit IgG
Molecular Weight	61 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Parafibromin;Cell division cycle protein 73 homolog;Hyperparathyroidism 2 protein;CDC73;C1orf28, HRPT2;
Tissue Specificity	Found in adrenal and parathyroid glands, kidney and heart. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q6P1J9
Gene Id	79577
Gene Name	CDC73
Sequence	Belongs to the CDC73 family.
Subcellular Location	Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human

Reference	1. "Entrez Gene: CDC73 Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)". 2. Sood R, Bonner TI, Makalowska I, Stephan DA, Robbins CM, Connors TD, Morgenbesser SD, Su K, Faruque MU, Pinkett H, Graham C, Baxevanis AD, Klinger KW, Landes GM, Trent JM, Carpten JD (April 2001). "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus". Genomics 73 (2): 21122.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000428-1	PB9532	100 ug	-	$370		Add to Cart
BHA21000428-2	PB9532-10ug	10 ug	Sample	$99		Add to Cart
BHA21000428-3	PB9532-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000428-4	PB9532-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000428-5	PB9532-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000428-6	PB9532-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000428-7	PB9532-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000428-8	PB9532-FITC	100 ug	FITC	$570		Add to Cart
BHA21000428-9	PB9532-HRP	100 ug	HRP	$570		Add to Cart
BHA21000428-10	PB9532-APC	100 ug	APC	$670		Add to Cart
BHA21000428-11	PB9532-PE	100 ug	PE	$670		Add to Cart
BHA21000428-12	PB9532-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000428-13	PB9532-carrier-free	100 ug	carrier-free	$370		Add to Cart

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