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Home / Primary Antibodies / Polyclonal Antibodies

Anti-HNF1/HNF1A Antibody Picoband®

SKU : BHA21000120

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Mfr.No.	PB9214, PB9214-10ug, PB9214-Biotin, PB9214-Cy3, PB9214-Dylight488, PB9214-Dylight550, PB9214-Dylight594, PB9214-FITC, PB9214-HRP, PB9214-APC, PB9214-PE, PB9214-iFluor647, PB9214-carrier-free
Alternative Names	Hepatocyte nuclear factor 1-alpha
Background	HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What s more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-HNF1/HNF1A Antibody Picoband® catalog # PB9214. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'- GTTAATNATTAAC-3
Host	Rabbit
Immunogen Region	E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.
Isotype	Rabbit IgG
Molecular Weight	80 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Hepatocyte nuclear factor 1-alpha;HNF-1-alpha;HNF-1A;Liver-specific transcription factor LF-B1;LFB1;Transcription factor 1;TCF-1;HNF1A;TCF1;
Tissue Specificity	Liver.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P20823
Gene Id	6927
Gene Name	HNF1A
Sequence	Belongs to the HNF1 homeobox family.
Subcellular Location	Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human

Reference	1. Courtois, G., Morgan, J. G., Campbell, L. A., Fourel, G., Crabtree, G. R. Interaction of a liver-specific nuclear factor with the fibrinogen and alpha-1-antitrypsin promoters. Science 238: 688-692, 1987. 2. Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (June 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics 13 (2): 293300. 3. Vaxillaire M, Boccio V, Philippi A, Vigouroux C, Terwilliger J, Passa P, Beckmann JS, Velho G, Lathrop GM, Froguel P (April 1995). "A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q". Nat. Genet. 9 (4): 41823.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000120-1	PB9214	100 ug	-	$370		Add to Cart
BHA21000120-2	PB9214-10ug	10 ug	Sample	$99		Add to Cart
BHA21000120-3	PB9214-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000120-4	PB9214-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000120-5	PB9214-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000120-6	PB9214-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000120-7	PB9214-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000120-8	PB9214-FITC	100 ug	FITC	$570		Add to Cart
BHA21000120-9	PB9214-HRP	100 ug	HRP	$570		Add to Cart
BHA21000120-10	PB9214-APC	100 ug	APC	$670		Add to Cart
BHA21000120-11	PB9214-PE	100 ug	PE	$670		Add to Cart
BHA21000120-12	PB9214-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000120-13	PB9214-carrier-free	100 ug	carrier-free	$370		Add to Cart

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