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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Hex/HHEX Antibody Picoband®

SKU : BHA21000532

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Mfr.No.	PB9631, PB9631-10ug, PB9631-Biotin, PB9631-Cy3, PB9631-Dylight488, PB9631-Dylight550, PB9631-Dylight594, PB9631-FITC, PB9631-HRP, PB9631-APC, PB9631-PE, PB9631-iFluor647, PB9631-carrier-free
Alternative Names	Hematopoietically-expressed homeobox protein HHEX
Background	Hematopoietically-expressed homeobox protein HHEX is a protein that in humans is encoded by the HHEX gene. Homeobox genes are members of a family of transcription factors that regulate tissue development in many different organisms. Hromas et al. (1993) set out to identify homeobox genes that might play a role in hematopoiesis. And using somatic cell hybrid analysis, they mapped the HHEX gene to chromosome 10, where the HOX11 gene is located. Homeobox genes are involved in neoplastic transformation of both epithelial and hemopoietic tissues. The divergent homeobox gene HEX is expressed in the anterior visceral endoderm during early mouse development and in some adult tissues of endodermal origin, including liver and thyroid. D'Elia et al. s findings suggested that regulation of HEX entry in the nucleus of thyrocytes may represent a critical step during human thyroid tumorigenesis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Hex/HHEX Antibody Picoband® catalog # PB9631. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts lat
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human Hex, different from the related mouse sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	40 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Hematopoietically-expressed homeobox protein HHEX;Homeobox protein HEX;Homeobox protein PRH;HHEX;HEX, PRH, PRHX;
Tissue Specificity	Liver and promyelocytic leukemia cell line HL- 60. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q03014
Gene Id	3087
Gene Name	HHEX
Sequence	Contains 1 HMG box DNA-binding domain.
Subcellular Location	Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat

Reference	1. D'Elia, A. V., Tell, G., Russo, D., Arturi, F., Puglisi, F., Manfioletti, G., Gattei, V., Mack, D. L., Cataldi, P., Filetti, S., Di Loreto, C., Damante, G. Expression and localization of the homeodomain-containing protein HEX in human thyroid tumors. J. Clin. Endocr. Metab. 87: 1376-1383, 2002. 2. Hromas, R., Radich, J., Collins, S. PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells. Biochem. Biophys. Res. Commun. 195: 976-983, 1993.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000532-1	PB9631	100 ug	-	$370		Add to Cart
BHA21000532-2	PB9631-10ug	10 ug	Sample	$99		Add to Cart
BHA21000532-3	PB9631-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000532-4	PB9631-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000532-5	PB9631-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000532-6	PB9631-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000532-7	PB9631-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000532-8	PB9631-FITC	100 ug	FITC	$570		Add to Cart
BHA21000532-9	PB9631-HRP	100 ug	HRP	$570		Add to Cart
BHA21000532-10	PB9631-APC	100 ug	APC	$670		Add to Cart
BHA21000532-11	PB9631-PE	100 ug	PE	$670		Add to Cart
BHA21000532-12	PB9631-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000532-13	PB9631-carrier-free	100 ug	carrier-free	$370		Add to Cart

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