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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Hepatocyte growth factor HGF Antibody Picoband®

SKU : BHA21000257

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Mfr.No.	RP1062, RP1062-10ug, RP1062-Biotin, RP1062-Cy3, RP1062-Dylight488, RP1062-Dylight550, RP1062-Dylight594, RP1062-FITC, RP1062-HRP, RP1062-APC, RP1062-PE, RP1062-iFluor647, RP1062-carrier-free
Alternative Names	Hepatocyte growth factor
Background	Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. This gene is mapped to 7q21.11. It is secreted by mesenchymal cells and targets and acts primarily uponepithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration and in wound healing. HGF can regulate cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. HGF also serves as a paracrine mediator to control placental development and growth. HGF was identified as one of the liver sinusoidal endothelial cell-derived paracrine mediators promoting hepatocyte growth.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Hepatocyte growth factor HGF Antibody catalog # RP1062. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting i
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of mouse HGF, different from the related human sequence by five amino acids, and from the related rat sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	34 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Hepatocyte growth factor;Hepatopoietin-A;Scatter factor;SF;Hepatocyte growth factor alpha chain;Hepatocyte growth factor beta chain;Hgf;
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q08048
Gene Id	15234
Gene Name	HGF
Sequence	Belongs to the peptidase S1 family. Plasminogen subfamily.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse

Reference	1. Bottaro DP, Rubin JS, Faletto DL, Chan AM, Kmiecik TE, Vande Woude GF, Aaronson SA (February 1991). "Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product". Science251 (4995): 8024. 2. Gallagher, J.T., Lyon, M. (2000). "Molecular structure of Heparan Sulfate and interactions with growth factors and morphogens". In Iozzo, M, V. Proteoglycans: structure, biology and molecular interactions. Marcel Dekker Inc. New York, New York. pp. 2759. 3. LeCouter, J., Moritz, D. R., Li, B., Phillips, G. L., Liang, X. H., Gerber, H.-P., Hillan, K. J., Ferrara, N. Angiogenesis-independent endothelial protection of liver: role of VEGFR-1. Science 299: 890-893, 2003.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000257-1	RP1062	100 ug	-	$370		Add to Cart
BHA21000257-2	RP1062-10ug	10 ug	Sample	$99		Add to Cart
BHA21000257-3	RP1062-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000257-4	RP1062-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000257-5	RP1062-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000257-6	RP1062-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000257-7	RP1062-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000257-8	RP1062-FITC	100 ug	FITC	$570		Add to Cart
BHA21000257-9	RP1062-HRP	100 ug	HRP	$570		Add to Cart
BHA21000257-10	RP1062-APC	100 ug	APC	$670		Add to Cart
BHA21000257-11	RP1062-PE	100 ug	PE	$670		Add to Cart
BHA21000257-12	RP1062-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000257-13	RP1062-carrier-free	100 ug	carrier-free	$370		Add to Cart

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