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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GTPBP9/OLA1 Antibody Picoband®

SKU : BHA21005144

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Mfr.No.	A07162, A07162-10ug, A07162-Biotin, A07162-Cy3, A07162-Dylight488, A07162-Dylight550, A07162-Dylight594, A07162-FITC, A07162-HRP, A07162-APC, A07162-PE, A07162-iFluor647, A07162-carrier-free
Alternative Names	fatty acid binding protein 6
Background	Obg-like ATPase 1 is an enzyme that in humans is encoded by the OLA1 gene. This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has been observed in multiple types of cancer and may be associated with poor survival. Pseudogenes of this gene have been defined on chromosomes 17 and 22.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GTPBP9/OLA1 Antibody Picoband® catalog # A07162. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes. In vitro binds to bile acids in the order: deoxycholic acid > cholic acid &
Host	Rabbit
Immunogen Region	E.coli-derived human GTPBP9/OLA1 recombinant protein (Position: D8-D379).
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Gastrotropin; GT; Fatty acid-binding protein 6; Ileal lipid-binding protein; ILBP; Intestinal 15 kDa protein; I-15P; Intestinal bile acid-binding protein; I-BABP; FABP6; ILBP; ILLBP
Tissue Specificity	Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9NTK5
Gene Id	29789
Gene Name	OLA1
Subcellular Location	Cytoplasm. Membrane. Peripheral membrane protein. Cytoplasmic side.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25 ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Ding, Z., Liu, Y., Rubio, V., He, J., Minze, L. J., Shi, Z.-Z. OLA1, a translational regulator of p21, maintains optimal cell proliferation necessary for developmental progression. Molec. Cell. Biol. 36: 2568-2582, 2016.<br /><br />2. Koller-Eichho, R., Marquardt, T., Gail, R., Wittinghofer, A., Kostrewa, D., Kutay, U., Kambach, C. Human OLA1 defines an ATPase subfamily in the OBG family of GTP-binding proteins. J. Biol. Chem. 282: 19928-19937, 2007. (PubMed: 17430889, related citations) (Full Text)<br /><br />3. Scott, A. F. Personal Communication. Baltimore, Md. 6/29/2007.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005144-1	A07162	-	100 ug	$370		Add to Cart
BHA21005144-2	A07162-10ug	Sample	10 ug	$99		Add to Cart
BHA21005144-3	A07162-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005144-4	A07162-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005144-5	A07162-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005144-6	A07162-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005144-7	A07162-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005144-8	A07162-FITC	FITC	100 ug	$570		Add to Cart
BHA21005144-9	A07162-HRP	HRP	100 ug	$570		Add to Cart
BHA21005144-10	A07162-APC	APC	100 ug	$670		Add to Cart
BHA21005144-11	A07162-PE	PE	100 ug	$670		Add to Cart
BHA21005144-12	A07162-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005144-13	A07162-carrier-free	carrier-free	100 ug	$370		Add to Cart

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