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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GST3/GST pi/GSTP1 Antibody Picoband®

SKU : BHA21006631

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Mfr.No.	PA1040, PA1040-10ug, PA1040-Biotin, PA1040-Cy3, PA1040-Dylight488, PA1040-Dylight550, PA1040-Dylight594, PA1040-FITC, PA1040-HRP, PA1040-APC, PA1040-PE, PA1040-iFluor647, PA1040-carrier-free
Alternative Names	Glutathione S-transferase P
Background	Glutathione S-transferases pi, also known as GST3, present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. The GST-pi gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. The GST-pi gene is mapped to chromosome 11 .Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. GSTP does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-GST3/GST pi/GSTP1 Antibody catalog # PA1040. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human GST3, different from the related mouse sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	23 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Glutathione S-transferase P;2.5.1.18;GST class-pi;GSTP1-1;GSTP1;FAEES3, GST3;
Tissue Specificity	Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P09211
Gene Name	GSTP1
Sequence	Belongs to the GST superfamily. Pi family.
Subcellular Location	Cytoplasm . Mitochondrion . Nucleus . The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br>

Reference	1. Morrow, C. S.; Cowan, K. H.; Goldsmith, M. E. : Structure of the human genomic glutathione S-transferase-pi gene. Gene 75: 3-11, 1989<br /><br />2. Islam, M. Q.; Platz, A.; Szpirer, J.; Szpirer, C.; Levan, G.; Mannervik, B. : Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi. Hum. Genet. 82: 338-342, 1989. <br /><br />3. Konohana, A.; Konohana, I.; Schroeder, W. T.; O'Brien, W. R.; Amagai, M.; Greer, J.; Shimizu, N.; Gammon, W. R.; Siciliano, M. J.; Duvic, M. :Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. J. Invest. Derm. 95: 119-126, 1990.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006631-1	PA1040	-	100 ug	$370		Add to Cart
BHA21006631-2	PA1040-10ug	Sample	10 ug	$99		Add to Cart
BHA21006631-3	PA1040-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006631-4	PA1040-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006631-5	PA1040-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006631-6	PA1040-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006631-7	PA1040-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006631-8	PA1040-FITC	FITC	100 ug	$570		Add to Cart
BHA21006631-9	PA1040-HRP	HRP	100 ug	$570		Add to Cart
BHA21006631-10	PA1040-APC	APC	100 ug	$670		Add to Cart
BHA21006631-11	PA1040-PE	PE	100 ug	$670		Add to Cart
BHA21006631-12	PA1040-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006631-13	PA1040-carrier-free	carrier-free	100 ug	$370		Add to Cart

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