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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GRK5 Antibody Picoband®

SKU : BHA21000608

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Mfr.No.	PB9708, PB9708-10ug, PB9708-Biotin, PB9708-Cy3, PB9708-Dylight488, PB9708-Dylight550, PB9708-Dylight594, PB9708-FITC, PB9708-HRP, PB9708-APC, PB9708-PE, PB9708-iFluor647, PB9708-carrier-free
Alternative Names	G protein-coupled receptor kinase 5
Background	G protein-coupled receptor kinase 5 is an enzyme that in humans is encoded by the GRK5 gene. It is mapped to 10q26.11. This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-GRK5 Antibody Picoband® catalog # PB9708. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein- coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, intealization, and signaling ev
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human GRK5, different from the related mouse and rat sequences by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	68 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	G protein-coupled receptor kinase 5;2.7.11.16;G protein-coupled receptor kinase GRK5;GRK5;GPRK5;
Tissue Specificity	Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P34947
Gene Id	2869
Gene Name	GRK5
Subcellular Location	Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Predominantly localized at the plasma membrane; targeted to the cell surface through the interaction with phospholipids. Nucleus localization is regulated in a GPCR and Ca (2+)/calmodulin-dependent fashion.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat

Reference	1. "Entrez Gene: GRK5 G protein-coupled receptor kinase 5". 2. Bullrich F, Druck T, Kunapuli P, et al. (1995). "Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.". Cytogenet. Cell Genet. 70 (34): 2504. 3. Kunapuli P, Benovic JL (Jul 1993). "Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family". Proc Natl Acad Sci U S A 90 (12): 558892.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000608-1	PB9708	100 ug	-	$370		Add to Cart
BHA21000608-2	PB9708-10ug	10 ug	Sample	$99		Add to Cart
BHA21000608-3	PB9708-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000608-4	PB9708-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000608-5	PB9708-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000608-6	PB9708-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000608-7	PB9708-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000608-8	PB9708-FITC	100 ug	FITC	$570		Add to Cart
BHA21000608-9	PB9708-HRP	100 ug	HRP	$570		Add to Cart
BHA21000608-10	PB9708-APC	100 ug	APC	$670		Add to Cart
BHA21000608-11	PB9708-PE	100 ug	PE	$670		Add to Cart
BHA21000608-12	PB9708-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000608-13	PB9708-carrier-free	100 ug	carrier-free	$370		Add to Cart

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