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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Granzyme M/GZMM Antibody Picoband®

SKU : BHA21003569

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Mfr.No.	A08286-1, A08286-1-10ug, A08286-1-Biotin, A08286-1-Cy3, A08286-1-Dylight488, A08286-1-Dylight550, A08286-1-Dylight594, A08286-1-FITC, A08286-1-HRP, A08286-1-APC, A08286-1-PE, A08286-1-iFluor647, A08286-1-carrier-free
Alternative Names	neuropeptides B and W receptor 1
Background	Granzyme M is a protein that in humans is encoded by the GZMM gene. Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Granzyme M/GZMM Antibody Picoband® catalog # A08286-1. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Host	Rabbit
Immunogen Region	E.coli-derived mouse Granzyme M/GZMM recombinant protein (Position: A64-D206).
Isotype	Rabbit IgG
Molecular Weight	28 kDa
Reactivity	Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Neuropeptides B/W receptor type 1; G-protein coupled receptor 7; NPBWR1; GPR7
Tissue Specificity	Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	O08643
Gene Id	16904
Gene Name	Gzmm
Subcellular Location	Cell membrane. Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Mouse ELISA, 0.1-0.5 ug/ml, -

Reference	1. Pao, L. I., Sumaria, N., Kelly, J. M., van Dommelen, S., Cretney, E., Wallace, M. E., Anthony, D. A., Uldrich, A. P., Godfrey, D. I., Papadimitriou, J. M., Mullbacher, A., Degli-Esposti, M. A., Smyth, M. J. Functional analysis of granzyme M and its role in immunity to infection. J. Immun. 175: 3235-3243, 2005. 2. Pilat, D., Fink, T., Obermaier-Skrobanek, B., Zimmer, M., Wekerle, H., Lichter, P., Jenne, D. E. The human Met-ase gene (GZMM): structure, sequence, and close physical linkage to the serine protease gene cluster on 19p13.3. Genomics 24: 445-450, 1994.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003569-1	A08286-1	-	100 ug	$370		Add to Cart
BHA21003569-2	A08286-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003569-3	A08286-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003569-4	A08286-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003569-5	A08286-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003569-6	A08286-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003569-7	A08286-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003569-8	A08286-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003569-9	A08286-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003569-10	A08286-1-APC	APC	100 ug	$670		Add to Cart
BHA21003569-11	A08286-1-PE	PE	100 ug	$670		Add to Cart
BHA21003569-12	A08286-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003569-13	A08286-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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