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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GHITM Antibody Picoband®

SKU : BHA21003683

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Mfr.No.	A11256-1, A11256-1-10ug, A11256-1-Biotin, A11256-1-Cy3, A11256-1-Dylight488, A11256-1-Dylight550, A11256-1-Dylight594, A11256-1-FITC, A11256-1-HRP, A11256-1-APC, A11256-1-PE, A11256-1-iFluor647, A11256-1-carrier-free
Alternative Names	interleukin 17B
Background	Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 orDERP2, is a mitochondrial protein which localizes in the inner membrane.GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GHITM Antibody Picoband® catalog # A11256-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .
Host	Rabbit
Immunogen Region	E.coli-derived human GHITM recombinant protein (Position: M1-K345).
Isotype	Rabbit IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7
Tissue Specificity	Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9H3K2
Gene Id	27069
Gene Name	GHITM
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Gross, M. B. Personal Communication. Baltimore, Md. 2/23/2021. 2. Lisak, D. A., Schacht, T., Enders, V., Habicht, J., Kiviluoto, S., Scheider, J., Henke, N., Bultynck, G., Methner, A. The transmembrane Bax inhibitor motif (TMBIM) containing protein family: tissue expression, intracellular localization and effects on the ER Ca(2+)-filling state. Biochim. Biophys. Acta 1853: 2104-2114, 2015. 3. Oka, T., Sayano, T., Tamai, S., Yokota, S., Kato, H., Fujii, G., Mihara, K. Identification of a novel protein MICS1 that is involved in maintenance of mitochondrial morphology and apoptotic release of cytochrome c. Molec. Biol. Cell 19: 2597-2608, 2008.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003683-1	A11256-1	-	100 ug	$370		Add to Cart
BHA21003683-2	A11256-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003683-3	A11256-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003683-4	A11256-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003683-5	A11256-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003683-6	A11256-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003683-7	A11256-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003683-8	A11256-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003683-9	A11256-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003683-10	A11256-1-APC	APC	100 ug	$670		Add to Cart
BHA21003683-11	A11256-1-PE	PE	100 ug	$670		Add to Cart
BHA21003683-12	A11256-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003683-13	A11256-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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