JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-GCSF Receptor/CSF3R Antibody Picoband®

SKU : BHA21007154

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PA1906, PA1906-10ug, PA1906-Biotin, PA1906-Cy3, PA1906-Dylight488, PA1906-Dylight550, PA1906-Dylight594, PA1906-FITC, PA1906-HRP, PA1906-APC, PA1906-PE, PA1906-iFluor647, PA1906-carrier-free
Alternative Names	Granulocyte colony-stimulating factor receptor
Background	CSF3R (Colony-Stimulating Factor 3 Receptor, Granulocyte) also known as GCSFR or CD114 ( (Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. The CSF3R gene consists of 17 exons. By in situ hybridization using human CSF3R cDNA as a probe, Inazawa et al. (1991) localized the gene to 1p35-p34.3. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2. Dong et al. (2001) reported that the C terminus of CSF3R is required for SHP1 downregulation of CSF3-induced STAT activation. The authors proposed that this mechanism inhibits cell proliferation and survival in response to CSF3.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-GCSF Receptor/CSF3R Antibody catalog # PA1906. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human GCSF Receptor.
Isotype	Rabbit IgG
Molecular Weight	108 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Granulocyte colony-stimulating factor receptor;G-CSF receptor;G-CSF-R;CD114;CSF3R;GCSFR;
Tissue Specificity	One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q99062
Gene Name	CSF3R
Sequence	Belongs to the type I cytokine receptor family. Type 2 subfamily.
Subcellular Location	Isoform 2: Secreted .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Dong, F., Qiu, Y., Yi, T., Touw, I. P., Laer, A. C. The carboxyl terminus of the granulocyte colony-stimulating factor receptor, truncated in patients with severe congenital neutropenia/acute myeloid leukemia, is required for SH2-containing phosphatase-1 suppression of Stat activation. J. Immun. 167: 6447-6452, 2001. <br /><br />2. Inazawa, J., Fukunaga, R., Seto, Y., Nakagawa, H., Misawa, S., Abe, T., Nagata, S. Assignment of the human granulocyte colony-stimulating factor receptor gene (CSF3R) to chromosome 1 at region p35-p34.3. Genomics 10: 1075-1078, 1991.<br /><br />3. Plo, I., Zhang, Y., Le Couedic, J.-P., Nakatake, M., Boulet, J.-M., Itaya, M., Smith, S. O., Debili, N., Constantinescu, S. N., Vainchenker, W., Louache, F., de Botton, S. An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia. J. Exp. Med. 206: 1701-1707, 2009.<br /><br />

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007154-1	PA1906	-	100 ug	$370		Add to Cart
BHA21007154-2	PA1906-10ug	Sample	10 ug	$99		Add to Cart
BHA21007154-3	PA1906-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007154-4	PA1906-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007154-5	PA1906-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007154-6	PA1906-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007154-7	PA1906-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007154-8	PA1906-FITC	FITC	100 ug	$570		Add to Cart
BHA21007154-9	PA1906-HRP	HRP	100 ug	$570		Add to Cart
BHA21007154-10	PA1906-APC	APC	100 ug	$670		Add to Cart
BHA21007154-11	PA1906-PE	PE	100 ug	$670		Add to Cart
BHA21007154-12	PA1906-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007154-13	PA1906-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.