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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GATA3 Antibody Picoband®

SKU : BHA21000109

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Mfr.No.	PB9199, PB9199-10ug, PB9199-Biotin, PB9199-Cy3, PB9199-Dylight488, PB9199-Dylight550, PB9199-Dylight594, PB9199-FITC, PB9199-HRP, PB9199-APC, PB9199-PE, PB9199-iFluor647, PB9199-carrier-free
Alternative Names	Trans-acting T-cell-specific transcription factor GATA-3
Background	Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-GATA3 Antibody Picoband® catalog # PB9199. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. .
Host	Rabbit
Immunogen Region	E.coli-derived human GATA3 recombinant protein (Position: M1-E197). Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.
Isotype	Rabbit IgG
Molecular Weight	48 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Trans-acting T-cell-specific transcription factor GATA-3;GATA-binding factor 3;GATA3;
Tissue Specificity	T-cells and endothelial cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P23771
Gene Id	2625
Gene Name	GATA3
Sequence	Contains 2 GATA-type zinc fingers.
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat

Reference	1. Joulin V, Bories D, Eleouet JF, Labastie MC, Chretien S, Mattei MG, Romeo PH (Jul 1991). "A T-cell specific TCR delta DNA binding protein is a member of the human GATA family" 2. Kouros-Mehr Hosein, Slorach EM, Stelicht MD, Werb Z (December 2006). "GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland". Cell 127 (5): 104155. 3. Wilson BJ (2008). "Does GATA3 act in tissue-specific pathways A meta-analysis-based approach". J. Carcinogenesis 7: 6.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000109-1	PB9199	100 ug	-	$370		Add to Cart
BHA21000109-2	PB9199-10ug	10 ug	Sample	$99		Add to Cart
BHA21000109-3	PB9199-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000109-4	PB9199-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000109-5	PB9199-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000109-6	PB9199-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000109-7	PB9199-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000109-8	PB9199-FITC	100 ug	FITC	$570		Add to Cart
BHA21000109-9	PB9199-HRP	100 ug	HRP	$570		Add to Cart
BHA21000109-10	PB9199-APC	100 ug	APC	$670		Add to Cart
BHA21000109-11	PB9199-PE	100 ug	PE	$670		Add to Cart
BHA21000109-12	PB9199-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000109-13	PB9199-carrier-free	100 ug	carrier-free	$370		Add to Cart

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