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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GARS1 Antibody Picoband®

SKU : BHA21006205

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Mfr.No.	A04618-2, A04618-2-10ug, A04618-2-Biotin, A04618-2-Cy3, A04618-2-Dylight488, A04618-2-Dylight550, A04618-2-Dylight594, A04618-2-FITC, A04618-2-HRP, A04618-2-APC, A04618-2-PE, A04618-2-iFluor647, A04618-2-carrier-free
Background	GlycinetRNA ligase also known as glycyltRNA synthetase is an enzyme that in humans is encoded by the GARS1 gene. This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Description	Boster Bio Anti-GARS1 Antibody Picoband® catalog # A04618-2. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived human GARS1 recombinant protein (Position: E61-D673). Human GARS1 shares 95.3% and 95.4% amino acid (aa) sequence identity with mouse and rat GARS1, respectively.
Molecular Weight	80 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P41250
Gene Id	2617
Gene Name	GARS1

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Abe, A., Hayasaka, K. The GARS gene is rarely mutated in Japanese patients with Charcot-Marie-Tooth neuropathy. J. Hum. Genet. 54: 310-312, 2009. 2. Antonellis, A., Ellsworth, R. E., Sambuughin, N., Puls, I., Abel, A., Lee-Lin, S.-Q., Jordanova, A., Kremensky, I., Christodoulou, K., Middleton, L. T., Sivakumar, K., Ionasescu, V., Funalot, B., Vance, J. M., Goldfarb, L. G., Fischbeck, K. H., Green, E. D. Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V. Am. J. Hum. Genet. 72: 1293-1299, 2003. 3. Boczonadi, V., Meyer, K., Gonczarowska-Jorge, H., Griffin, H., Roos, A., Bartsakoulia, M., Bansagi, B., Ricci, G., Palinkas, F., Zahedi, R. P., Bruni, F., Kaspar, B., Lochmuller, H., Boycott, K. M., Muller, J. S., Horvath, R. Mutations in glycyl-tRNA synthetase impair mitochondrial metabolism in neurons. Hum. Molec. Genet. 27: 2187-2204, 2018.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006205-1	A04618-2	-	100 ug	$370		Add to Cart
BHA21006205-2	A04618-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21006205-3	A04618-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006205-4	A04618-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006205-5	A04618-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006205-6	A04618-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006205-7	A04618-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006205-8	A04618-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21006205-9	A04618-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21006205-10	A04618-2-APC	APC	100 ug	$670		Add to Cart
BHA21006205-11	A04618-2-PE	PE	100 ug	$670		Add to Cart
BHA21006205-12	A04618-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006205-13	A04618-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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