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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GAP43 Antibody Picoband®

SKU : BHA21002617

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Mfr.No.	A01868, A01868-10ug, A01868-Biotin, A01868-Cy3, A01868-Dylight488, A01868-Dylight550, A01868-Dylight594, A01868-FITC, A01868-HRP, A01868-APC, A01868-PE, A01868-iFluor647, A01868-carrier-free
Alternative Names	growth associated protein 43
Background	Growth Associated Protein 43 (GAP43) is a protein encoded by the GAP43 gene in humans. It is mapped to 3q13.31. The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alteatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GAP43 Antibody Picoband® catalog # A01868. Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human GAP43, which shares 95.2% amino acid (aa) sequence identity with both mouse and rat GAP43.
Isotype	Rabbit IgG
Molecular Weight	38-43 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46; GAP43
Tissue Specificity	Isoform 1 and isoform 2 are expressed in liver, colon and small intestine. Isoform 2 but not isoform 1 is expressed in kidney. Isoform 1 and isoform 2 are not expressed in esophagus. Not expressed in skin.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P17677
Gene Id	2596
Gene Name	GAP43
Subcellular Location	Cell membrane. Peripheral membrane protein. Cytoplasmic side. Growth cone membrane. Filopodium membrane. Synapse. Perikaryon. Dendrite. Axon. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, WB
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Rat<br> Immunofluorescence, 5ug/ml, Rat<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Kosik, K. S., Orecchio, L. D., Bruns, G. A. P., Benowitz, L. I., MacDonald, G. P., Cox, D. R., Neve, R. L. Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human. Neuron 1: 127-132, 1988.<br /><br />2. Reeves, R. H., O'Hara, B. F., Gearhart, J. D. Localization on mouse chromosome 16 of Smst and Gap43: a conserved synteny with human chromosome 3. (Abstract) Cytogenet. Cell Genet. 51: 1064, 1989.<br /><br />3. Strittmatter, S. M., Fankhauser, C., Huang, P. L., Mashimo, H., Fishman, M. C. Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell 80: 445-452, 1995.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002617-1	A01868	-	100 ug	$370		Add to Cart
BHA21002617-2	A01868-10ug	Sample	10 ug	$99		Add to Cart
BHA21002617-3	A01868-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002617-4	A01868-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002617-5	A01868-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002617-6	A01868-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002617-7	A01868-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002617-8	A01868-FITC	FITC	100 ug	$570		Add to Cart
BHA21002617-9	A01868-HRP	HRP	100 ug	$570		Add to Cart
BHA21002617-10	A01868-APC	APC	100 ug	$670		Add to Cart
BHA21002617-11	A01868-PE	PE	100 ug	$670		Add to Cart
BHA21002617-12	A01868-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002617-13	A01868-carrier-free	carrier-free	100 ug	$370		Add to Cart

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