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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Galectin 1 Lgals1 Antibody

SKU : BHA21001392

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Mfr.No.	A00470-2, A00470-2-10ug, A00470-2-Biotin, A00470-2-Cy3, A00470-2-Dylight488, A00470-2-Dylight550, A00470-2-Dylight594, A00470-2-FITC, A00470-2-HRP, A00470-2-APC, A00470-2-PE, A00470-2-iFluor647, A00470-2-carrier-free
Alternative Names	lectin, galactose binding, soluble 1
Background	Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Galectin 1 Lgals1 Antibody Picoband® catalog # A00470-2. Tested in ELISA applications. This antibody reacts with Mouse.
Function	Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.
Host	Rabbit
Immunogen Region	E. coli-derived mouse Galectin 1 recombinant protein (Position: A2-E135).
Isotype	Rabbit IgG
Molecular Weight	15 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Galectin-1; Gal-1; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; S-Lac lectin 1; Lgals1; Gbp;
Tissue Specificity	Widespread; most predominant in spleen, lung and prostate.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Lgals1: P16045
Gene Id	16852
Gene Name	Lgals1
Subcellular Location	Secreted, extracellular space, extracellular matrix

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA
Description	ELISA Capture (Matched Antibody Pair), 2-8ug/ml<br>

Reference	1. Das, K., Lin, Y., Widen, E., Zhang, Y., Scherer, P. E. Chromosomal localization, expression patte, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochem. Biophys. Res. Commun. 280: 1120-1129, 2001.<br /><br />2. Schaffler, A., Orso, E., Palitzsch, K.-D., Buchler, C., Drobnik, W., Furst, A., Scholmerich, J., Schmitz, G. The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH). Biochem. Biophys. Res. Commun. 260: 416-425, 1999.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001392-1	A00470-2	100 ug	-	$370		Add to Cart
BHA21001392-2	A00470-2-10ug	10 ug	Sample	$99		Add to Cart
BHA21001392-3	A00470-2-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001392-4	A00470-2-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001392-5	A00470-2-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001392-6	A00470-2-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001392-7	A00470-2-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001392-8	A00470-2-FITC	100 ug	FITC	$570		Add to Cart
BHA21001392-9	A00470-2-HRP	100 ug	HRP	$570		Add to Cart
BHA21001392-10	A00470-2-APC	100 ug	APC	$670		Add to Cart
BHA21001392-11	A00470-2-PE	100 ug	PE	$670		Add to Cart
BHA21001392-12	A00470-2-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001392-13	A00470-2-carrier-free	100 ug	carrier-free	$370		Add to Cart

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