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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Galactosidase alpha/Gla Antibody Picoband®

SKU : BHA21001130

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Mfr.No.	A01135, A01135-10ug, A01135-Biotin, A01135-Cy3, A01135-Dylight488, A01135-Dylight550, A01135-Dylight594, A01135-FITC, A01135-HRP, A01135-APC, A01135-PE, A01135-iFluor647, A01135-carrier-free
Alternative Names	Alpha-galactosidase A
Background	Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Galactosidase alpha/Gla Antibody Picoband® catalog # A01135. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alteate pathway. Its function is homologous to that of C1s in the classical pathway.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of mouse Gla, different from the related human sequence by fifteen amino acids.
Isotype	Rabbit IgG
Molecular Weight	49 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Alpha-galactosidase A;3.2.1.22 ;Alpha-D-galactosidase A;Alpha-D-galactoside galactohydrolase;Melibiase;Gla;Ags;
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P51569
Gene Id	11605
Gene Name	Gla
Subcellular Location	Lysosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat<br>

Reference	1. "Entrez Gene: GLA galactosidase, alpha".<br /><br />2. Calhoun DH, Bishop DF, Bestein HS, Quinn M, Hantzopoulos P, Desnick RJ (1985). "Fabry disease: isolation of a cDNA clone encoding human alpha-galactosidase A". Proceedings of the National Academy of Sciences of the United States of America. 82 (21): 73648.<br /><br />3. Keating GM (October 2012). "Agalsidase alfa: a review of its use in the management of Fabry disease". BioDrugs. 26 (5): 33554.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001130-1	A01135	100 ug	-	$370		Add to Cart
BHA21001130-2	A01135-10ug	10 ug	Sample	$99		Add to Cart
BHA21001130-3	A01135-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001130-4	A01135-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001130-5	A01135-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001130-6	A01135-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001130-7	A01135-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001130-8	A01135-FITC	100 ug	FITC	$570		Add to Cart
BHA21001130-9	A01135-HRP	100 ug	HRP	$570		Add to Cart
BHA21001130-10	A01135-APC	100 ug	APC	$670		Add to Cart
BHA21001130-11	A01135-PE	100 ug	PE	$670		Add to Cart
BHA21001130-12	A01135-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001130-13	A01135-carrier-free	100 ug	carrier-free	$370		Add to Cart

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