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Home / Primary Antibodies / Polyclonal Antibodies

Anti-FXYD1 Antibody Picoband®

SKU : BHA21000604

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Mfr.No.	PB9704, PB9704-10ug, PB9704-Biotin, PB9704-Cy3, PB9704-Dylight488, PB9704-Dylight550, PB9704-Dylight594, PB9704-FITC, PB9704-HRP, PB9704-APC, PB9704-PE, PB9704-iFluor647, PB9704-carrier-free
Alternative Names	Phospholemman
Background	Phospholemman is a protein that in humans is encoded by the FXYD1 gene. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. Transcript variants with different 5' UTR sequences have been described in the literature.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-FXYD1 Antibody Picoband® catalog # PB9704. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.
Host	Rabbit
Immunogen Region	E.coli-derived human FXYD1 recombinant protein (Position: E21-R92). Human FXYD1 shares 86.1% and 87.5% amino acid (aa) sequence identity with mouse and rat FXYD1, respectively.
Isotype	Rabbit IgG
Molecular Weight	10 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Phospholemman;FXYD domain-containing ion transport regulator 1;FXYD1;PLM;
Tissue Specificity	Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	O00168
Gene Id	5348
Gene Name	FXYD1
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat

Reference	1. "Entrez Gene: FXYD1 FXYD domain containing ion transport regulator 1 (phospholemman)". 2. Chen LS, Lo CF, Numann R, Cuddy M (Jul 1997). "Characterization of the human and rat phospholemman (PLM) cDNAs and localization of the human PLM gene to chromosome 19q13.1". Genomics 41 (3): 43543.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000604-1	PB9704	100 ug	-	$370		Add to Cart
BHA21000604-2	PB9704-10ug	10 ug	Sample	$99		Add to Cart
BHA21000604-3	PB9704-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000604-4	PB9704-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000604-5	PB9704-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000604-6	PB9704-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000604-7	PB9704-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000604-8	PB9704-FITC	100 ug	FITC	$570		Add to Cart
BHA21000604-9	PB9704-HRP	100 ug	HRP	$570		Add to Cart
BHA21000604-10	PB9704-APC	100 ug	APC	$670		Add to Cart
BHA21000604-11	PB9704-PE	100 ug	PE	$670		Add to Cart
BHA21000604-12	PB9704-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000604-13	PB9704-carrier-free	100 ug	carrier-free	$370		Add to Cart

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