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Home / Primary Antibodies / Polyclonal Antibodies

Anti-FXR2 Antibody Picoband®

SKU : BHA21004334

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Mfr.No.	A05130-4, A05130-4-10ug, A05130-4-Biotin, A05130-4-Cy3, A05130-4-Dylight488, A05130-4-Dylight550, A05130-4-Dylight594, A05130-4-FITC, A05130-4-HRP, A05130-4-APC, A05130-4-PE, A05130-4-iFluor647, A05130-4-carrier-free
Alternative Names	Sodium- and chloride-dependent GABA transporter 1
Background	Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-FXR2 Antibody Picoband® catalog # A05130-4. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Host	Rabbit
Immunogen Region	E.coli-derived human FXR2 recombinant protein (Position: N153-K651).
Isotype	Rabbit IgG
Molecular Weight	93 kDa
Reactivity	Human, Monkey, Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Sodium- and chloride-dependent GABA transporter 1;GAT-1;Solute carrier family 6 member 1;SLC6A1;GABATR, GABT1, GAT1;
Tissue Specificity	Expressed in many tissues, highest levels in skeletal muscle.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P51116
Gene Id	9513
Gene Name	FXR2
Subcellular Location	Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of inteeurons (By similarity). .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Monkey<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human, Mouse<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Bontekoe, C. J. M., McIlwain, K. L., Nieuwenhuizen, I. M., Yuva-Paylor, L. A., Nellis, A., Willemsen, R., Fang, Z., Kirkpatrick, L., Bakker, C. E., McAninch, R., Cheng, N. C., Merriweather, M., Hoogeveen, A. T., Nelson, D., Paylor, R., Oostra, B. A. Knockout mouse model for Fxr2: a model for mental retardation. Hum. Molec. Genet. 11: 487-498, 2002. <br /><br />2. Daell, J. C., Fraser, C. E., Mostovetsky, O., Daell, R. B. Discrimination of common and unique RNA-binding activities among fragile X mental retardation protein paralogs. Hum. Molec. Genet. 18: 3164-3177, 2009.<br /><br />3. Kirkpatrick, L. L., McIlwain, K. A., Nelson, D. L. Comparative genomic sequence analysis of the FXR gene family: FMR1, FXR1, and FXR2. Genomics 78: 169-177, 2001.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004334-1	A05130-4	-	100 ug	$370		Add to Cart
BHA21004334-2	A05130-4-10ug	Sample	10 ug	$99		Add to Cart
BHA21004334-3	A05130-4-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004334-4	A05130-4-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004334-5	A05130-4-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004334-6	A05130-4-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004334-7	A05130-4-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004334-8	A05130-4-FITC	FITC	100 ug	$570		Add to Cart
BHA21004334-9	A05130-4-HRP	HRP	100 ug	$570		Add to Cart
BHA21004334-10	A05130-4-APC	APC	100 ug	$670		Add to Cart
BHA21004334-11	A05130-4-PE	PE	100 ug	$670		Add to Cart
BHA21004334-12	A05130-4-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004334-13	A05130-4-carrier-free	carrier-free	100 ug	$370		Add to Cart

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