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Home / Primary Antibodies / Polyclonal Antibodies

Anti-FOXRED2 Antibody Picoband®

SKU : BHA21003951

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Mfr.No.	A12703-1, A12703-1-10ug, A12703-1-Biotin, A12703-1-Cy3, A12703-1-Dylight488, A12703-1-Dylight550, A12703-1-Dylight594, A12703-1-FITC, A12703-1-HRP, A12703-1-APC, A12703-1-PE, A12703-1-iFluor647, A12703-1-carrier-free
Alternative Names	histone cluster 1 H3 family member a/b/c/d/e/f/g/h/i/j
Background	FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-FOXRED2 Antibody Picoband® catalog # A12703-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replic
Host	Rabbit
Immunogen Region	E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).
Isotype	Rabbit IgG
Molecular Weight	80 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/I; Histone H3/j; Histone H3/k; Histone H3/l; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; H3FJ
Tissue Specificity	Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q8IWF2
Gene Id	80020
Gene Name	FOXRED2
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat ELISA, 0.1-0.5 ug/ml, -

Reference	1. Hartz, P. A. Personal Communication. Baltimore, Md. 2/25/2011. 2. Riemer, J., Appenzeller-Herzog, C., Johansson, L., Bodenmiller, B., Hartmann-Petersen, R., Ellgaard, L. A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proc. Nat. Acad. Sci. 106: 14831-14836, 2009.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003951-1	A12703-1	-	100 ug	$370		Add to Cart
BHA21003951-2	A12703-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003951-3	A12703-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003951-4	A12703-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003951-5	A12703-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003951-6	A12703-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003951-7	A12703-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003951-8	A12703-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003951-9	A12703-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003951-10	A12703-1-APC	APC	100 ug	$670		Add to Cart
BHA21003951-11	A12703-1-PE	PE	100 ug	$670		Add to Cart
BHA21003951-12	A12703-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003951-13	A12703-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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