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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Fibroblast growth factor 2 FGF2 Antibody Picoband®

SKU : BHA21006581

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Mfr.No.	RP1006, RP1006-10ug, RP1006-Biotin, RP1006-Cy3, RP1006-Dylight488, RP1006-Dylight550, RP1006-Dylight594, RP1006-FITC, RP1006-HRP, RP1006-APC, RP1006-PE, RP1006-iFluor647, RP1006-carrier-free
Alternative Names	Fibroblast growth factor 2
Background	FGF2 has been implicated in a multitude of physiologic and pathologic processes, including limb development, angiogenesis, wound healing, and tumor growth. Human FGF2 shares 96% and 97% amino acid sequence homology with mouse and rat respectively. FGF2 belongs to the fibroblast growth factor (FGF) family. Fibroblast growth factors (FGFs) exhibit widespread mitogenic and neurotrophic activities. Nine members of the family are currently known, and FGF-1 and FGF-2 are present in relatively high levels in CNS. FGF-2 is expressed by at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Fibroblast growth factor 2 FGF2 Antibody catalog # RP1006. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. .
Host	Rabbit
Immunogen Region	E.coli-derived human FGF2 recombinant protein (Position: P143-S288).
Isotype	Rabbit IgG
Molecular Weight	17-21 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Fibroblast growth factor 2;FGF-2;Basic fibroblast growth factor;bFGF;Heparin-binding growth factor 2;HBGF-2;FGF2;FGFB;
Tissue Specificity	Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P09038
Gene Name	FGF2
Sequence	Belongs to the heparin-binding growth factors family.
Subcellular Location	Secreted. Nucleus. Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IF, ICC, WB, Flow Cytometry
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry(Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Doniach, T. : Basic FGF as an inducer of anteroposterior neural patte. Cell 83: 1067-1070, 1995.<br /><br />2. Eckenstein, F. P. : Fibroblast growth factors in the nervous system. J. Neurobiol. 25: 1467-1480, 1994.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006581-1	RP1006	-	100 ug	$370		Add to Cart
BHA21006581-2	RP1006-10ug	Sample	10 ug	$99		Add to Cart
BHA21006581-3	RP1006-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006581-4	RP1006-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006581-5	RP1006-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006581-6	RP1006-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006581-7	RP1006-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006581-8	RP1006-FITC	FITC	100 ug	$570		Add to Cart
BHA21006581-9	RP1006-HRP	HRP	100 ug	$570		Add to Cart
BHA21006581-10	RP1006-APC	APC	100 ug	$670		Add to Cart
BHA21006581-11	RP1006-PE	PE	100 ug	$670		Add to Cart
BHA21006581-12	RP1006-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006581-13	RP1006-carrier-free	carrier-free	100 ug	$370		Add to Cart

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