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Home / Primary Antibodies / Polyclonal Antibodies

Anti-FES Antibody Picoband®

SKU : BHA21007116

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Mfr.No.	PA1854-1, PA1854-1-10ug, PA1854-1-Biotin, PA1854-1-Cy3, PA1854-1-Dylight488, PA1854-1-Dylight550, PA1854-1-Dylight594, PA1854-1-FITC, PA1854-1-HRP, PA1854-1-APC, PA1854-1-PE, PA1854-1-iFluor647, PA1854-1-carrier-free
Alternative Names	Tyrosine-protein kinase Fes/Fps
Background	FES (feline sarcoma oncogene) is an enzyme that in humans is encoded by the FES gene, also known as Proto-oncogene tyrosine-protein kinase Fes/Fps, Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, p93c-fes c-fes/fps protein, FPS, Oncogene FES, feline sarcoma virus, FPS. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. Non-onc intervening sequences were present in the human counterpart. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia, but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-FES Antibody catalog # PA1854-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon rece
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human FES, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	93 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Tyrosine-protein kinase Fes/Fps;2.7.10.2;Feline sarcoma/Fujinami avian sarcoma oncogene homolog;Proto-oncogene c-Fes;Proto-oncogene c-Fps;p93c-fes;FES;FPS;
Tissue Specificity	Widely expressed. Detected in adult colon epithelium. .
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2mg Na2HPO4.

Uniprot	P07332
Gene Name	FES
Sequence	Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
Subcellular Location	Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Golgi apparatus. Cell junction, focal adhesion. Distributed throughout the cytosol when the kinase is not activated. Association with microtubules requires activation of the kinase activity. Shuttles between focal adhesions and cell-cell contacts in epithelial cells. Recruited to the lateral cell membrane in polarized epithelial cells by interaction with phosphorylated EZR. Detected at tubular membrane structures in the cytoplasm and at the cell periphery.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Dalla-Favera, R., Franchini, G., Martinotti, S., Wong-Staal, F., Gallo, R. C., Croce, C. M. Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis virus onc genes. Proc. Nat. Acad. Sci. 79: 4714-4717, 1982.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007116-1	PA1854-1	-	100 ug	$370		Add to Cart
BHA21007116-2	PA1854-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21007116-3	PA1854-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007116-4	PA1854-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007116-5	PA1854-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007116-6	PA1854-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007116-7	PA1854-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007116-8	PA1854-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21007116-9	PA1854-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21007116-10	PA1854-1-APC	APC	100 ug	$670		Add to Cart
BHA21007116-11	PA1854-1-PE	PE	100 ug	$670		Add to Cart
BHA21007116-12	PA1854-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007116-13	PA1854-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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