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Home / Primary Antibodies / Polyclonal Antibodies

Anti-FABP4 Antibody Picoband®

SKU : BHA21001239

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Mfr.No.	A01528, A01528-10ug, A01528-Biotin, A01528-Cy3, A01528-Dylight488, A01528-Dylight550, A01528-Dylight594, A01528-FITC, A01528-HRP, A01528-APC, A01528-PE, A01528-iFluor647, A01528-carrier-free
Alternative Names	Fatty acid-binding protein, adipocyte
Background	Fatty acid binding proteins (FABPs) are small cytoplasmic proteins that are expressed in a highly tissue-specific manner and bind to fatty acids such as oleic and retinoic acid. Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient mice have shown that this lipid chaperone has a significant role in several aspects of metabolic syndrome, including type 2 diabetes and atherosclerosis. It regulates allergic airway inflammation and may provide a link between fatty acid metabolism and asthma.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-FABP4 Antibody Picoband® catalog # A01528. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). .
Host	Rabbit
Immunogen Region	E. coli-derived rat FABP4 recombinant protein (Position: C2-A132). Rat FABP4 shares 88.5% and 93.9% amino acid (aa) sequence identity with human and mouse FABP4, respectively.
Isotype	Rabbit IgG
Molecular Weight	15 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Fatty acid-binding protein, adipocyte;Adipocyte lipid-binding protein;ALBP;Adipocyte-type fatty acid-binding protein;A-FABP;AFABP;Fatty acid-binding protein 4;Fabp4;
Tissue Specificity	Expressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P70623
Gene Id	79451
Gene Name	Fabp4
Subcellular Location	Cytoplasm. Nucleus. Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity). .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat<br> ELISA, 0.1-0.5ug/ml,<br>

Reference	1. Hotamisligil, G. S.; Johnson, R. S.; Distel, R. J.; Ellis, R.; Papaioannou, V. E.; Spiegelman, B. M. : Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274: 1377-1379, 1996. <br /><br />2. Furuhashi, M.; Tuncman, G.; Gorgun, C. Z.; Makowski, L.; Atsumi, G.; Vaillancourt, E.; Kono, K.; Babaev, V. R.; Fazio, S.; Linton, M. F.; Sulsky, R.; Robl, J. A.; Parker, R. A.; Hotamisligil, G. S. : Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 447: 959-965, 2007. <br /><br />3. Shum, B. O. V.; Mackay, C. R.; Gorgun, C. Z.; Frost, M. J.; Kumar, R. K.; Hotamisligil, G. S.; Rolph, M. S. : The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation. J. Clin. Invest. 116: 2183-2192, 2006.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001239-1	A01528	100 ug	-	$370		Add to Cart
BHA21001239-2	A01528-10ug	10 ug	Sample	$99		Add to Cart
BHA21001239-3	A01528-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001239-4	A01528-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001239-5	A01528-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001239-6	A01528-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001239-7	A01528-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001239-8	A01528-FITC	100 ug	FITC	$570		Add to Cart
BHA21001239-9	A01528-HRP	100 ug	HRP	$570		Add to Cart
BHA21001239-10	A01528-APC	100 ug	APC	$670		Add to Cart
BHA21001239-11	A01528-PE	100 ug	PE	$670		Add to Cart
BHA21001239-12	A01528-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001239-13	A01528-carrier-free	100 ug	carrier-free	$370		Add to Cart

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