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Home / Primary Antibodies / Polyclonal Antibodies

Anti-EPS15 Antibody Picoband®

SKU : BHA21001636

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Mfr.No.	A01681, A01681-10ug, A01681-Biotin, A01681-Cy3, A01681-Dylight488, A01681-Dylight550, A01681-Dylight594, A01681-FITC, A01681-HRP, A01681-APC, A01681-PE, A01681-iFluor647, A01681-carrier-free
Alternative Names	epidermal growth factor receptor pathway substrate 15
Background	Epidermal growth factor receptor substrate 15 is a protein that in humans is encoded by the EPS15 gene. This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alteative splicing results in multiple transcript variants encoding distinct isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-EPS15 Antibody Picoband® catalog # A01681. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the intealization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Pla
Host	Rabbit
Immunogen Region	E. coli-derived human EPS15 recombinant protein (Position: A2-E88).
Isotype	Rabbit IgG
Molecular Weight	140 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Epidermal growth factor receptor substrate 15; Protein Eps15; Protein AF-1p; EPS15; AF1P
Tissue Specificity	Ubiquitously expressed.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P42566
Gene Id	2060
Gene Name	EPS15
Subcellular Location	Cytoplasm. Cell membrane; Recruited to the plasma membrane upon EGFR activation and localizes to coated pits. Colocalizes with UBQLN1 in ubiquitin- rich cytoplasmic aggregates that are not endocytic compartments and in cytoplasmic juxtanuclear structures called aggresomes.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. "Entrez Gene: EPS15 epidermal growth factor receptor pathway substrate 15".<br /><br />2. Wong WT, Kraus MH, Carlomagno F, Zelano A, Druck T, Croce CM, Huebner K, Di Fiore PP (Jun 1994). "The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32". Oncogene. 9 (6): 15917.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001636-1	A01681	100 ug	-	$370		Add to Cart
BHA21001636-2	A01681-10ug	10 ug	Sample	$99		Add to Cart
BHA21001636-3	A01681-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001636-4	A01681-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001636-5	A01681-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001636-6	A01681-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001636-7	A01681-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001636-8	A01681-FITC	100 ug	FITC	$570		Add to Cart
BHA21001636-9	A01681-HRP	100 ug	HRP	$570		Add to Cart
BHA21001636-10	A01681-APC	100 ug	APC	$670		Add to Cart
BHA21001636-11	A01681-PE	100 ug	PE	$670		Add to Cart
BHA21001636-12	A01681-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001636-13	A01681-carrier-free	100 ug	carrier-free	$370		Add to Cart

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