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Home / Primary Antibodies / Polyclonal Antibodies

Anti-EGR1 Antibody Picoband®

SKU : BHA21004126

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Mfr.No.	A00687-3, A00687-3-10ug, A00687-3-Biotin, A00687-3-Cy3, A00687-3-Dylight488, A00687-3-Dylight550, A00687-3-Dylight594, A00687-3-FITC, A00687-3-HRP, A00687-3-APC, A00687-3-PE, A00687-3-iFluor647, A00687-3-carrier-free
Alternative Names	early growth response 1
Background	Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct patte of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-EGR1 Antibody Picoband® catalog # A00687-3. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcriptional regulator (PubMed:20121949). Recognizes and binds to the DNA sequence 5'-GCG (T/G)GGGCG-3' (EGR-site) in the promoter region of target genes (By similarity). Binds double- stranded target DNA, irrespective of the cytosine methylation statu
Host	Rabbit
Immunogen Region	E.coli-derived human EGR1 recombinant protein (Position: A2-M38).
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Early growth response protein 1
Tissue Specificity	Detected in neutrophils (at protein level).
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P18146
Gene Id	1958
Gene Name	EGR1
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, Flow Cytometry, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human, Mouse, Rat<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Das, A., Chendil, D., Dey, S., Mohiuddin, M., Mohiuddin, M., Milbrandt, J., Rangnekar, V. M., Ahmed, M. M. Ionizing radiation down-regulates p53 protein in primary Egr-1(-/-) mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. J. Biol. Chem. 276: 3279-3286, 2001.<br /><br />2. Joslin, J. M., Feald, A. A., Tennant, T. R., Davis, E. M., Kogan, S. C., Anastasi, J., Crispino, J. D., Le Beau, M. M. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood 110: 719-726, 2007.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004126-1	A00687-3	-	100 ug	$370		Add to Cart
BHA21004126-2	A00687-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21004126-3	A00687-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004126-4	A00687-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004126-5	A00687-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004126-6	A00687-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004126-7	A00687-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004126-8	A00687-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21004126-9	A00687-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21004126-10	A00687-3-APC	APC	100 ug	$670		Add to Cart
BHA21004126-11	A00687-3-PE	PE	100 ug	$670		Add to Cart
BHA21004126-12	A00687-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004126-13	A00687-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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