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Home / Primary Antibodies / Polyclonal Antibodies

Anti-DRD5 Antibody Picoband®

SKU : BHA21006214

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Mfr.No.	A03010-1, A03010-1-10ug, A03010-1-Biotin, A03010-1-Cy3, A03010-1-Dylight488, A03010-1-Dylight550, A03010-1-Dylight594, A03010-1-FITC, A03010-1-HRP, A03010-1-APC, A03010-1-PE, A03010-1-iFluor647, A03010-1-carrier-free
Background	D(1B) dopamine receptor(DRD5), also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.
Clonality	Polyclonal
Description	Boster Bio Anti-DRD5 Antibody Picoband® catalog # A03010-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived human DRD5 recombinant protein (Position: M1-H477). Human DRD5 shares 82.3% and 82.4% amino acid (aa) sequence identity with mouse and rat DRD5, respectively.
Molecular Weight	58 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P21918
Gene Id	1816
Gene Name	DRD5

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Li, H., Armando, I., Yu, P., Escano, C., Mueller, S. C., Asico, L., Pascua, A., Lu, Q., Wang, X., Villar, V. A. M., Jones, J. E., Wang, Z., and 9 others. Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells. J. Clin. Invest. 118: 2180-2189, 2008. Note: Erratum: J. Clin. Invest. 118: 2986 only, 2008. 2. Lowe, N., Kirley, A., Hawi, Z., Sham, P., Wickham, H., Kratochvil, C. J., Smith, S. D., Lee, S. Y., Levy, F., Kent, L., Middle, F., Rohde, L. A., and 20 others. Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. Am. J. Hum. Genet. 74: 348-356, 2004. 3. Misbahuddin, A., Placzek, M. R., Chaudhuri, K. R., Wood, N. W., Bhatia, K. P., Waer, T. T. A polymorphism in the dopamine receptor DRD5 is associated with blepharospasm. Neurology 58: 124-126, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006214-1	A03010-1	-	100 ug	$370		Add to Cart
BHA21006214-2	A03010-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21006214-3	A03010-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006214-4	A03010-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006214-5	A03010-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006214-6	A03010-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006214-7	A03010-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006214-8	A03010-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21006214-9	A03010-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21006214-10	A03010-1-APC	APC	100 ug	$670		Add to Cart
BHA21006214-11	A03010-1-PE	PE	100 ug	$670		Add to Cart
BHA21006214-12	A03010-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006214-13	A03010-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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