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Home / Primary Antibodies / Polyclonal Antibodies

Anti-DKK2 Antibody Picoband®

SKU : BHA21000447

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Mfr.No.	PB9551, PB9551-10ug, PB9551-Biotin, PB9551-Cy3, PB9551-Dylight488, PB9551-Dylight550, PB9551-Dylight594, PB9551-FITC, PB9551-HRP, PB9551-APC, PB9551-PE, PB9551-iFluor647, PB9551-carrier-free
Alternative Names	Dickkopf-related protein 2
Background	Dickkopf-related protein 2 is a protein that in humans is encoded by the DKK2 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-DKK2 Antibody Picoband® catalog # PB9551. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a teary complex with the transmembrane protein KREMEN that promotes intealization of LRP5/6. DKKs play an important role in vertebrate development, where they
Host	Rabbit
Immunogen Region	E.coli-derived human DKK2 recombinant protein (Position: K34-I259). Human DKK2 shares 96% amino acid (aa) sequence identity with mouse DKK2.
Isotype	Rabbit IgG
Molecular Weight	28 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Dickkopf-related protein 2;Dickkopf-2;Dkk-2;hDkk-2;DKK2;UNQ682/PRO1316;
Tissue Specificity	Expressed in heart, brain, skeletal muscle and lung.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9UBU2
Gene Id	27123
Gene Name	DKK2
Sequence	Belongs to the DAXX family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat

Reference	1. "Entrez Gene: DKK2 dickkopf homolog 2 (Xenopus laevis)". 2. Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (Dec 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene 238 (2): 30113. 3. Wu W, Glinka A, Delius H, Niehrs C (2001). "Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling.". Curr. Biol. 10 (24): 16114.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000447-1	PB9551	100 ug	-	$370		Add to Cart
BHA21000447-2	PB9551-10ug	10 ug	Sample	$99		Add to Cart
BHA21000447-3	PB9551-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000447-4	PB9551-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000447-5	PB9551-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000447-6	PB9551-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000447-7	PB9551-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000447-8	PB9551-FITC	100 ug	FITC	$570		Add to Cart
BHA21000447-9	PB9551-HRP	100 ug	HRP	$570		Add to Cart
BHA21000447-10	PB9551-APC	100 ug	APC	$670		Add to Cart
BHA21000447-11	PB9551-PE	100 ug	PE	$670		Add to Cart
BHA21000447-12	PB9551-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000447-13	PB9551-carrier-free	100 ug	carrier-free	$370		Add to Cart

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