JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-Desmoglein 3/DSG3 Antibody Picoband®

SKU : BHA21006894

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PA1567, PA1567-10ug, PA1567-Biotin, PA1567-Cy3, PA1567-Dylight488, PA1567-Dylight550, PA1567-Dylight594, PA1567-FITC, PA1567-HRP, PA1567-APC, PA1567-PE, PA1567-iFluor647, PA1567-carrier-free
Alternative Names	Desmoglein-3
Background	Desmoglein3 is also known as PVA (Pemphigus Vulgaris Antigen). Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune diseases of the skin which have as target antigens 2 different members of the desmoglein subfamily of the desmosomal cadherins: pemphigus vulgaris antigen (PVA, or desmoglein-3) in the case of PV and desmoglein I in the case of PF. The DSG3 gene, like the genes for DSG1 and DSG2, is located on chromosome 18. The human DSG3 gene consists of 15 exons and spans more than 23 kb. DSG3 and DSG1 are the autoantigens of pemphigus vulgaris and pemphigus foliaceus, respectively. DSG3 and DSG1 are the target antigens in PNP, and IgG autoantibodies against DSG3 in PNP sera play a pathogenic role in the loss of keratinocyte adhesion and blistering.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Desmoglein 3/DSG3 Antibody catalog # PA1567. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 3.
Isotype	Rabbit IgG
Molecular Weight	130 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Desmoglein-3;130 kDa pemphigus vulgaris antigen;PVA;Cadherin family member 6;DSG3;CDHF6;
Tissue Specificity	Epidermis, tongue, tonsil, esophagus and carcinomas.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P32926
Gene Name	DSG3
Sequence	Belongs to the SCF family.
Subcellular Location	Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Amagai, M., Klaus-Kovtun, V., Stanley, J. R.Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion.Cell 67: 869-877, 1991.<br /><br />2. Aemann, J., Spurr, N. K., Buxton, R. S.The human gene (DSG3) coding for the pemphigus vulgaris antigen is, like the genes coding for the other two known desmogleins, assigned to chromosome 18.Hum. Genet. 89: 347-350, 1992.<br /><br />3. Silos, S. A., Tamai, K., Li, K., Kivirikko, S., Kouba, D., Christiano, A. M., Uitto, J.Cloning of the gene for human pemphigus vulgaris antigen (desmoglein 3), a desmosomal cadherin.J. Biol. Chem. 271: 17504-17511, 1996.<br /><br />

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006894-1	PA1567	-	100 ug	$370		Add to Cart
BHA21006894-2	PA1567-10ug	Sample	10 ug	$99		Add to Cart
BHA21006894-3	PA1567-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006894-4	PA1567-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006894-5	PA1567-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006894-6	PA1567-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006894-7	PA1567-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006894-8	PA1567-FITC	FITC	100 ug	$570		Add to Cart
BHA21006894-9	PA1567-HRP	HRP	100 ug	$570		Add to Cart
BHA21006894-10	PA1567-APC	APC	100 ug	$670		Add to Cart
BHA21006894-11	PA1567-PE	PE	100 ug	$670		Add to Cart
BHA21006894-12	PA1567-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006894-13	PA1567-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.