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Home / Primary Antibodies / Polyclonal Antibodies

Anti-DDAH2 Antibody Picoband®

SKU : BHA21000906

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Mfr.No.	PB10001, PB10001-10ug, PB10001-Biotin, PB10001-Cy3, PB10001-Dylight488, PB10001-Dylight550, PB10001-Dylight594, PB10001-FITC, PB10001-HRP, PB10001-APC, PB10001-PE, PB10001-iFluor647, PB10001-carrier-free
Alternative Names	N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
Background	DDAH2 is known as dimethylarginine dimethylaminohydrolase 2 which is mapped to 6p21.3 by radiation hybrid and FISH analysis. This gene encodes a dimethylarginine dimethylaminohydrolase. DDAH2 functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in tu inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alteative splicing resulting in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-DDAH2 Antibody Picoband® catalog # PB10001. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Hydrolyzes N (G),N (G)-dimethyl-L-arginine (ADMA) and N (G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human DDAH2, different from the related mouse and rat sequences by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	24 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	N (G),N (G)-dimethylarginine dimethylaminohydrolase 2;DDAH-2;Dimethylarginine dimethylaminohydrolase 2;3.5.3.18;DDAHII;Dimethylargininase-2;Protein G6a;S-phase protein;DDAH2;DDAH, G6A, NG30;
Tissue Specificity	Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	O95865
Gene Id	23564
Gene Name	DDAH2
Sequence	Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
Subcellular Location	Cytoplasm . Mitochondrion . Translocates from cytosol to mitochondrion upon IL-1beta stimulation in chondrocytes.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Immunocytochemistry/Immunofluorescence, 2ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Leiper, J. M,, Santa Maria, J., Chubb, A., MacAllister, R. J., Charles, I. G., Whitley, G. S., Vallance, P. Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases.Biochem. J. 343: 209-214, 1999. 2. Smith, C. L., Birdsey, G. M., Anthony, S., Arrigoni, F. I., Leiper, J. M., Vallance, P. Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype. Biochem. Biophys. Res. Commun. 308: 984-989, 2003. 3. Tran, C. T. L., Fox, M. F., Vallance, P., Leiper, J. M. Chromosomal localization, gene structure, and expression patte of DDAH1: comparison with DDAH2 and implications for evolutionary origins. Genomics 68: 101-105, 2000.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000906-1	PB10001	100 ug	-	$370		Add to Cart
BHA21000906-2	PB10001-10ug	10 ug	Sample	$99		Add to Cart
BHA21000906-3	PB10001-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000906-4	PB10001-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000906-5	PB10001-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000906-6	PB10001-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000906-7	PB10001-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000906-8	PB10001-FITC	100 ug	FITC	$570		Add to Cart
BHA21000906-9	PB10001-HRP	100 ug	HRP	$570		Add to Cart
BHA21000906-10	PB10001-APC	100 ug	APC	$670		Add to Cart
BHA21000906-11	PB10001-PE	100 ug	PE	$670		Add to Cart
BHA21000906-12	PB10001-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000906-13	PB10001-carrier-free	100 ug	carrier-free	$370		Add to Cart

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