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Home / Primary Antibodies / Polyclonal Antibodies

Anti-DDAH1 Antibody Picoband®

SKU : BHA21000905

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Mfr.No.	PB10000, PB10000-10ug, PB10000-Biotin, PB10000-Cy3, PB10000-Dylight488, PB10000-Dylight550, PB10000-Dylight594, PB10000-FITC, PB10000-HRP, PB10000-APC, PB10000-PE, PB10000-iFluor647, PB10000-carrier-free
Alternative Names	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Background	DDAH1 is knowns as dimethylarginine dimethylaminohydrolase 1 which is mapped to chromosome 1p22 by radiation hybrid and FISH analysis. This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. DDAH1 plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in tu inhibit nitric oxide synthase activity. It widely expressed, especially in liver and kidney.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-DDAH1 Antibody Picoband® catalog # PB10000. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Hydrolyzes N (G),N (G)-dimethyl-L-arginine (ADMA) and N (G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human DDAH1, different from the related mouse and rat sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	31 kDa, 37 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	N (G),N (G)-dimethylarginine dimethylaminohydrolase 1;DDAH-1;Dimethylarginine dimethylaminohydrolase 1;3.5.3.18;DDAHI;Dimethylargininase-1;DDAH1;DDAH;
Tissue Specificity	Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	O94760
Gene Id	23576
Gene Name	DDAH1
Sequence	Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat, By Heat Immunocytochemistry/Immunofluorescence, 2ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Dayoub, H., Achan, V., Adimoolam, S., Jacobi, J., Stuehlinger, M. C., Wang, B., Tsao, P. S., Kimoto, M., Vallance, P., Patterson, A. J., Cooke, J. P. Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence.Circulation 108: 3042-3047, 2003. 2. Millatt, L. J., Whitley, G. StJ., Li, D., Leiper, J. M., Siragy, H. M., Carey, R. M., Johns, R. A. Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension. Circulation 108: 1493-1498, 2003. 3. Tran, C. T. L., Fox, M. F., Vallance, P., Leiper, J. M. Chromosomal localization, gene structure, and expression patte of DDAH1: comparison with DDAH2 and implications for evolutionary origins. Genomics 68: 101-105, 2000.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000905-1	PB10000	100 ug	-	$370		Add to Cart
BHA21000905-2	PB10000-10ug	10 ug	Sample	$99		Add to Cart
BHA21000905-3	PB10000-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000905-4	PB10000-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000905-5	PB10000-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000905-6	PB10000-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000905-7	PB10000-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000905-8	PB10000-FITC	100 ug	FITC	$570		Add to Cart
BHA21000905-9	PB10000-HRP	100 ug	HRP	$570		Add to Cart
BHA21000905-10	PB10000-APC	100 ug	APC	$670		Add to Cart
BHA21000905-11	PB10000-PE	100 ug	PE	$670		Add to Cart
BHA21000905-12	PB10000-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000905-13	PB10000-carrier-free	100 ug	carrier-free	$370		Add to Cart

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