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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Cytochrome P450 2U1 CYP2U1 Antibody Picoband®

SKU : BHA21007244

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Mfr.No.	PA2022, PA2022-10ug, PA2022-Biotin, PA2022-Cy3, PA2022-Dylight488, PA2022-Dylight550, PA2022-Dylight594, PA2022-FITC, PA2022-HRP, PA2022-APC, PA2022-PE, PA2022-iFluor647, PA2022-carrier-free
Alternative Names	Cytochrome P450 2U1
Background	CYP2U1 (Cytochrome P450, Family 2, Subfamily U, Polypeptide 1), is a protein that in humans is encoded by the CYP2U1 gene. Members of the P450 enzyme family have roles in the tissue-specific conversion of substrates into locally active hormones, <a href="https://www.bosterbio.com/blog/post/detecting-vitamins-in-laboratories" style="color:#EA8D28">vitamins</a>, and signaling molecules, including arachidonic acid derivatives known as eicosanoids. The Inteational Radiation Hybrid Mapping Consortium mapped the CYP2U1 gene to chromosome 4.Chuang et al. (2004) stated that CYP2U1 maps to 4q25. Using recombination experiments in Sf9 insect cells, Chuang et al. (2004) found that CYP2U1 metabolized arachidonic acid, docosahexaenoic acid (DHA), and other long chain fatty acids. Chuang et al. (2004) suggested that CYP2U1 may play a role in brain and immune functions.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Cytochrome P450 2U1 CYP2U1 Antibody catalog # PA2022. Tested in IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human CYP2U1.
Isotype	Rabbit IgG
Molecular Weight	22 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Cytochrome P450 2U1;1.14.14.1;CYP2U1;
Tissue Specificity	Widely expressed with stronger expression in thymus, heart and cerebellum. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q7Z449
Gene Name	CYP2U1
Sequence	Belongs to the G-protein coupled receptor 1 family.
Subcellular Location	Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, ICC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat <br>Immunocytochemistry , 0.5-1ug/ml, Human, -<br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Chuang, S. S., Helvig, C., Taimi, M., Ramshaw, H. A., Collop, A. H., Amad, M., White, J. A., Petkovich, M., Jones, G., Korczak, B. CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids. J. Biol. Chem. 279: 6305-6314, 2004. <br /><br />2. Tesson, C., Nawara, M., Salih, M. A. M., Rossignol, R., Zaki, M. S., Al Balwi, M., Schule, R., Mignot, C., Obre, E., Bouhouche, A., Santorelli, F. M., Durand, C. M., and 30 others. Alteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia. Am. J. Hum. Genet. 91: 1051-1064, 2012.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007244-1	PA2022	-	100 ug	$370		Add to Cart
BHA21007244-2	PA2022-10ug	Sample	10 ug	$99		Add to Cart
BHA21007244-3	PA2022-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007244-4	PA2022-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007244-5	PA2022-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007244-6	PA2022-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007244-7	PA2022-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007244-8	PA2022-FITC	FITC	100 ug	$570		Add to Cart
BHA21007244-9	PA2022-HRP	HRP	100 ug	$570		Add to Cart
BHA21007244-10	PA2022-APC	APC	100 ug	$670		Add to Cart
BHA21007244-11	PA2022-PE	PE	100 ug	$670		Add to Cart
BHA21007244-12	PA2022-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007244-13	PA2022-carrier-free	carrier-free	100 ug	$370		Add to Cart

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