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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CXCR2 Antibody Picoband®

SKU : BHA21006627

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Mfr.No.	PA1029, PA1029-10ug, PA1029-Biotin, PA1029-Cy3, PA1029-Dylight488, PA1029-Dylight550, PA1029-Dylight594, PA1029-FITC, PA1029-HRP, PA1029-APC, PA1029-PE, PA1029-iFluor647, PA1029-carrier-free
Alternative Names	C-X-C chemokine receptor type 2
Background	CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-CXCR2 Antibody catalog # PA1029. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human CXCR2, different from the related mouse sequence by six amino acids.
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	C-X-C chemokine receptor type 2;CXC-R2;CXCR-2;CDw128b;GRO/MGSA receptor;High affinity interleukin-8 receptor B;IL-8R B;IL-8 receptor type 2;CD182;CXCR2;IL8RB;
Tissue Specificity	Found in plasma.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P25025
Gene Name	CXCR2
Sequence	Belongs to the G-protein coupled receptor 1 family.
Subcellular Location	Cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat<br>

Reference	1. Murphy P.M., Tiffany H.L.;"Cloning of complementary DNA encoding a functional human interleukin-8 receptor."; Science 253:1280-1283(1991).<br /><br />2. Cerretti D.P., Kozlosky C.J., Vanden Bos T., Nelson N., Gearing D.P., Beckmann M.P.;<br /><br />"Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2."; Mol. Immunol. 30:359-367(1993).<br /><br />3. Sprenger H., Lloyd A.R., Lautens L.L., Bonner T.I., Kelvin D.J.;"Structure, genomic organization, and expression of the human interleukin-8 receptor B gene.";J. Biol. Chem. 269:11065-11072(1994).<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006627-1	PA1029	-	100 ug	$370		Add to Cart
BHA21006627-2	PA1029-10ug	Sample	10 ug	$99		Add to Cart
BHA21006627-3	PA1029-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006627-4	PA1029-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006627-5	PA1029-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006627-6	PA1029-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006627-7	PA1029-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006627-8	PA1029-FITC	FITC	100 ug	$570		Add to Cart
BHA21006627-9	PA1029-HRP	HRP	100 ug	$570		Add to Cart
BHA21006627-10	PA1029-APC	APC	100 ug	$670		Add to Cart
BHA21006627-11	PA1029-PE	PE	100 ug	$670		Add to Cart
BHA21006627-12	PA1029-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006627-13	PA1029-carrier-free	carrier-free	100 ug	$370		Add to Cart

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