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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CNTF Antibody Picoband®

SKU : BHA21007494

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Mfr.No.	PB9032, PB9032-10ug, PB9032-Biotin, PB9032-Cy3, PB9032-Dylight488, PB9032-Dylight550, PB9032-Dylight594, PB9032-FITC, PB9032-HRP, PB9032-APC, PB9032-PE, PB9032-iFluor647, PB9032-carrier-free
Alternative Names	Ciliary neurotrophic factor
Background	Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The mouse CNTF gene is on mouse chromosome 19 and that its expression is unaffected in the mouse neurologic mutant wobbler, a form of spinal muscular atrophy. The CNTF protein is highly conserved in evolution. The protein is a potent survival factor for neurons and oligodendrocytes, and it may be involved in reducing tissue destruction during inflammatory attacks. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-CNTF Antibody Picoband® catalog # PB9032. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Host	Rabbit
Immunogen Region	E.coli-derived mouse CNTF recombinant protein (Position: A2-M198). Mouse CNTF shares 83% and 95% amino acid (aa) sequences identity with human and rat CNTF, respectively.
Isotype	Rabbit IgG
Molecular Weight	29 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Ciliary neurotrophic factor;CNTF;Cntf;
Tissue Specificity	Nervous system.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P51642
Gene Id	12803
Gene Name	CNTF
Sequence	Belongs to the intercrine beta (chemokine CC) family.
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat, By Heat<br>

Reference	1. Lam, A., Fuller, F., Miller, J., Kloss, J., Manthorpe, M., Varon, S., Cordell, B. Sequence and structural organization of the human gene encoding ciliary neurotrophic factor. Gene 102: 271-276, 1991.<br /><br />2. Watt, M. J., Dzamko, N., Thomas, W. G., Rose-John, S., Est, M., Carling, D., Kemp, B. E., Febbraio, M. A., Steinberg, G. R. CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. Nature Med. 12: 541-548, 2006.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007494-1	PB9032	-	100 ug	$370		Add to Cart
BHA21007494-2	PB9032-10ug	Sample	10 ug	$99		Add to Cart
BHA21007494-3	PB9032-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007494-4	PB9032-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007494-5	PB9032-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007494-6	PB9032-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007494-7	PB9032-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007494-8	PB9032-FITC	FITC	100 ug	$570		Add to Cart
BHA21007494-9	PB9032-HRP	HRP	100 ug	$570		Add to Cart
BHA21007494-10	PB9032-APC	APC	100 ug	$670		Add to Cart
BHA21007494-11	PB9032-PE	PE	100 ug	$670		Add to Cart
BHA21007494-12	PB9032-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007494-13	PB9032-carrier-free	carrier-free	100 ug	$370		Add to Cart

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