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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CD89/FCAR Antibody Picoband®

SKU : BHA21003557

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Mfr.No.	A07546-1, A07546-1-10ug, A07546-1-Biotin, A07546-1-Cy3, A07546-1-Dylight488, A07546-1-Dylight550, A07546-1-Dylight594, A07546-1-FITC, A07546-1-HRP, A07546-1-APC, A07546-1-PE, A07546-1-iFluor647, A07546-1-carrier-free
Alternative Names	C-C motif chemokine ligand 16
Background	FCAR, Receptor for Fc fragment of IGA, is also known as CD89. Human Fc-alpha receptor(FCAR) is present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. FCAR interacts with aggregated IgAs, such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is a glycoprotein of 50 to 100 kD, with diversity on different cell types. FCAR is mapped to 19q13.4. Human COS cells transfected with FCAR cDNA bind to IgA, but not IgG.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-CD89/FCAR Antibody Picoband® catalog # A07546-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocyte
Host	Rabbit
Immunogen Region	E.coli-derived human CD89/FCAR recombinant protein (Position: Q22-K287).
Isotype	Rabbit IgG
Molecular Weight	32 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	C-C motif chemokine 16; Chemokine CC-4; HCC-4; Chemokine LEC; IL-10-inducible chemokine; LCC-1; Liver-expressed chemokine; Lymphocyte and monocyte chemoattractant; LMC; Monotactin-1; MTN-1; NCC-4; Small-inducible cytokine A16; CCL16; ILINCK; NCC4; SCYA16
Tissue Specificity	Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P24071
Gene Id	2204
Gene Name	FCAR
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Kremer, E. J., Kalatzis, V., Baker, E., Callen, D. F., Sutherland, G. R., Maliszewski, C. R.The gene for the human IgA Fc receptor maps to 19q13.4.Hum. Genet. 89: 107-108, 1992. 2. Maliszewski, C. R., March, C. J., Schoenbo, M. A., Gimpel, S., Shen, L.Expression cloning of a human Fc receptor for IgA.J. Exp. Med. 172: 1665-1672, 1990.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003557-1	A07546-1	-	100 ug	$370		Add to Cart
BHA21003557-2	A07546-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003557-3	A07546-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003557-4	A07546-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003557-5	A07546-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003557-6	A07546-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003557-7	A07546-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003557-8	A07546-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003557-9	A07546-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003557-10	A07546-1-APC	APC	100 ug	$670		Add to Cart
BHA21003557-11	A07546-1-PE	PE	100 ug	$670		Add to Cart
BHA21003557-12	A07546-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003557-13	A07546-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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