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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CD8 alpha/CD8A Antibody Picoband®

SKU : BHA21000140

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Mfr.No.	PB9249, PB9249-10ug, PB9249-Biotin, PB9249-Cy3, PB9249-Dylight488, PB9249-Dylight550, PB9249-Dylight594, PB9249-FITC, PB9249-HRP, PB9249-APC, PB9249-PE, PB9249-iFluor647, PB9249-carrier-free
Alternative Names	T-cell surface glycoprotein CD8 alpha chain
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-CD8 alpha/CD8A Antibody Picoband® catalog # PB9249. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
Host	Rabbit
Immunogen Region	E.coli-derived human CD8 alpha recombinant protein (Position: S22-A187). Human CD8 alpha shares 49% and 47% amino acid (aa) sequence identity with mouse and rat CD8 alpha, respectively.
Isotype	Rabbit IgG
Molecular Weight	55 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD8a;CD8A;MAL;
Tissue Specificity	Brain.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P01732
Gene Id	925
Gene Name	CD8A
Sequence	Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Weste blot, 0.1-0.5ug/ml, Human

Reference	1. Bowcock, A. M., Kavathas, P., Margolskee, R. F., Herzenberg, L., Cavalli-Sforza, L. L. An RFLP associated with pcDLeu2-14, a human T-cell differentiation antigen CD8 (Leu2) cDNA mapped to 2p12. Nucleic Acids Res. 14: 7817 only, 1986. 2. "Entrez Gene: CD8A CD8a molecule"

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000140-1	PB9249	100 ug	-	$370		Add to Cart
BHA21000140-2	PB9249-10ug	10 ug	Sample	$99		Add to Cart
BHA21000140-3	PB9249-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000140-4	PB9249-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000140-5	PB9249-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000140-6	PB9249-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000140-7	PB9249-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000140-8	PB9249-FITC	100 ug	FITC	$570		Add to Cart
BHA21000140-9	PB9249-HRP	100 ug	HRP	$570		Add to Cart
BHA21000140-10	PB9249-APC	100 ug	APC	$670		Add to Cart
BHA21000140-11	PB9249-PE	100 ug	PE	$670		Add to Cart
BHA21000140-12	PB9249-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000140-13	PB9249-carrier-free	100 ug	carrier-free	$370		Add to Cart

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