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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CD134/OX40/Tnfrsf4 Antibody Picoband®

SKU : BHA21001690

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Mfr.No.	A02495, A02495-10ug, A02495-Biotin, A02495-Cy3, A02495-Dylight488, A02495-Dylight550, A02495-Dylight594, A02495-FITC, A02495-HRP, A02495-APC, A02495-PE, A02495-iFluor647, A02495-carrier-free
Alternative Names	TNF receptor superfamily member 4
Background	Tumor necrosis factor receptor superfamily, member 4, also known as ACT35 or CD134, is a cell surface glycoprotein that was discovered through the production of a monoclonal antibody raised against the HUT-102 cell line. It belongs to the tumor necrosis factor receptor superfamily. CD134 was mapped to 1p36 by fluorescence in situ hybridization. CD134 is the primary receptor for feline immunodeficiency virus. And CD134 expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-CD134/OX40/Tnfrsf4 Antibody Picoband® catalog # A02495. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity). .
Host	Rabbit
Immunogen Region	E. coli-derived rat TNFRSF4 recombinant protein (Position: V20-L198).
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Tumor necrosis factor receptor superfamily member 4; MRC OX40; OX40 antigen; OX40L receptor; CD134; Tnfrsf4; Ox40; Txgp1l
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P15725
Gene Id	25572
Gene Name	Tnfrsf4
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Bansal-Pakala, P., Jember, A. G.-H., Croft, M. Signaling through OX40 (CD134) breaks peripheral T-cell tolerance. Nature Med. 7: 907-912, 2001.<br /><br />2. Humphreys, I. R., Walzl, G., Edwards, L., Rae, A., Hill, S., Hussell, T. A critical role for OX40 in T cell-mediated immunopathology during lung viral infection. J. Exp. Med. 198: 1237-1242, 2003.<br /><br />3. Jember, A. G.-H., Zuberi, R., Liu, F.-T., Croft, M. Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40. J. Exp. Med. 193: 387-392, 2001. <br /><br />4. Shimojima, M., Miyazawa, T., Ikeda, Y., McMonagle, E. L., Haining, H., Akashi, H., Takeuchi, Y., Hosie, M. J., Willett, B. J. Use of CD134 as a primary receptor by the feline immunodeficiency virus. Science 303: 1192-1195, 2004.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001690-1	A02495	100 ug	-	$370		Add to Cart
BHA21001690-2	A02495-10ug	10 ug	Sample	$99		Add to Cart
BHA21001690-3	A02495-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001690-4	A02495-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001690-5	A02495-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001690-6	A02495-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001690-7	A02495-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001690-8	A02495-FITC	100 ug	FITC	$570		Add to Cart
BHA21001690-9	A02495-HRP	100 ug	HRP	$570		Add to Cart
BHA21001690-10	A02495-APC	100 ug	APC	$670		Add to Cart
BHA21001690-11	A02495-PE	100 ug	PE	$670		Add to Cart
BHA21001690-12	A02495-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001690-13	A02495-carrier-free	100 ug	carrier-free	$370		Add to Cart

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