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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CCDC36 Antibody Picoband®

SKU : BHA21002133

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Mfr.No.	A14775, A14775-10ug, A14775-Biotin, A14775-Cy3, A14775-Dylight488, A14775-Dylight550, A14775-Dylight594, A14775-FITC, A14775-HRP, A14775-APC, A14775-PE, A14775-iFluor647, A14775-carrier-free
Alternative Names	coiled-coil domain containing 36
Background	CCDC36, also known as CT74 (cancer/testis antigen 74), is a 584 amino acid protein that contains coiled-coil domains and is expressed as three alteatively spliced isoforms. The gene encoding CCDC36 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-CCDC36 Antibody Picoband® catalog # A14775. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completio
Host	Rabbit
Immunogen Region	E.coli-derived human CCDC36 recombinant protein (Position: E172-N472).
Isotype	Rabbit IgG
Molecular Weight	66 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interactor of HORMAD1 protein 1; Cancer/testis antigen 74; CT74; Coiled-coil domain-containing protein 36; CCDC36; IHO1
Tissue Specificity	Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q8IYA8
Gene Id	339834
Gene Name	CCDC36
Subcellular Location	Chromosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 2ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Stanzione M., Baumann M., Papanikos F., Dereli I., Lange J., Ramlal A., Traenkner D., Shibuya H., de Massy B., Watanabe Y., Jasin M., Keeney S., Toth A. Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. Nat. Cell Biol. 18:1208-1220(2016)

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002133-1	A14775	-	100 ug	$370		Add to Cart
BHA21002133-2	A14775-10ug	Sample	10 ug	$99		Add to Cart
BHA21002133-3	A14775-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002133-4	A14775-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002133-5	A14775-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002133-6	A14775-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002133-7	A14775-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002133-8	A14775-FITC	FITC	100 ug	$570		Add to Cart
BHA21002133-9	A14775-HRP	HRP	100 ug	$570		Add to Cart
BHA21002133-10	A14775-APC	APC	100 ug	$670		Add to Cart
BHA21002133-11	A14775-PE	PE	100 ug	$670		Add to Cart
BHA21002133-12	A14775-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002133-13	A14775-carrier-free	carrier-free	100 ug	$370		Add to Cart

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