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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CaV1.3/CACNA1D Antibody Picoband®

SKU : BHA21007451

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Mfr.No.	PA2293, PA2293-10ug, PA2293-Biotin, PA2293-Cy3, PA2293-Dylight488, PA2293-Dylight550, PA2293-Dylight594, PA2293-FITC, PA2293-HRP, PA2293-APC, PA2293-PE, PA2293-iFluor647, PA2293-carrier-free
Alternative Names	Voltage-dependent L-type calcium channel subunit alpha-1D
Background	Cav1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. It is mapped to 3p21.1. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Alpha-1D subunit can mediate DHP-sensitive, high voltage-activated, long-lasting calcium channel activity. CACNA1D can form L-type calcium channels with negative activation thresholds which is essential for normal auditory function and controling of cardiac pacemaker activity.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-CaV1.3/CACNA1D Antibody catalog # PA2293. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell mo
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human CaV1.3, different from the related mouse and rat sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	245 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Voltage-dependent L-type calcium channel subunit alpha-1D;Calcium channel, L type, alpha-1 polypeptide, isoform 2;Voltage-gated calcium channel subunit alpha Cav1.3;CACNA1D;CACH3, CACN4, CACNL1A2, CCHL1A2;
Tissue Specificity	Expressed in pancreatic islets and in brain, where it has been seen in cerebral cortex, hippocampus, basal ganglia, habenula and thalamus. Expressed in the small cell lung carcinoma cell line SCC-9. No expression in skeletal muscle. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q01668
Gene Name	CACNA1D
Subcellular Location	Membrane ; Multi-pass membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Rat, Human, Mouse<br>

Reference	1. "Entrez Gene: CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit"<br /><br />2. Platzer, J., Engel, J., Schrott-Fischer, A., Stephan, K., Bova, S., Chen, H., Zheng, H., Striessnig, J. Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca(2+) channels. Cell 102: 89-97, 2000. <br /><br />3. Williams, M. E., Feldman, D. H., McCue, A. F., Brenner, R., Velicelebi, G., Ellis, S. B., Harpold, M. M. Structure and functional expression of alpha-1, alpha-2, and beta subunits of a novel human neuronal calcium channel subtype. Neuron 8: 71-84, 1992.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007451-1	PA2293	-	100 ug	$370		Add to Cart
BHA21007451-2	PA2293-10ug	Sample	10 ug	$99		Add to Cart
BHA21007451-3	PA2293-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007451-4	PA2293-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007451-5	PA2293-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007451-6	PA2293-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007451-7	PA2293-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007451-8	PA2293-FITC	FITC	100 ug	$570		Add to Cart
BHA21007451-9	PA2293-HRP	HRP	100 ug	$570		Add to Cart
BHA21007451-10	PA2293-APC	APC	100 ug	$670		Add to Cart
BHA21007451-11	PA2293-PE	PE	100 ug	$670		Add to Cart
BHA21007451-12	PA2293-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007451-13	PA2293-carrier-free	carrier-free	100 ug	$370		Add to Cart

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