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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Calretinin/CALB2 Antibody Picoband®

SKU : BHA21002632

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Mfr.No.	A04255, A04255-10ug, A04255-Biotin, A04255-Cy3, A04255-Dylight488, A04255-Dylight550, A04255-Dylight594, A04255-FITC, A04255-HRP, A04255-APC, A04255-PE, A04255-iFluor647, A04255-carrier-free
Alternative Names	calbindin 2
Background	Calretinin, also known as calbindin 2 (formerly 29 kDa calbindin), is a calcium-binding protein involved in calcium signaling. In humans, the calretinin protein is encoded by the CALB2 gene. It is mapped to 16q22.2. This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Calretinin/CALB2 Antibody Picoband® catalog # A04255. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Calretinin is a calcium-binding protein which is abundant in auditory neurons.
Host	Rabbit
Immunogen Region	E.coli-derived human Calretinin/CALB2 recombinant protein (Position: S59-Q90).
Isotype	Rabbit IgG
Molecular Weight	32 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Calretinin; CR; 29 kDa calbindin; CALB2; CAB29
Tissue Specificity	Brain.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P22676
Gene Id	794
Gene Name	CALB2
Subcellular Location	Cuticular plate. Cytosol. Nucleus. Synaptic membrane. Dendrite. Gap junction. Neuron projection. Parallel fiber to Purkinje cell synapse. Presynapse. Stereocilium. Synapse.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human, Rat<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Chen, L. Z., Harris, P. C., Apostolou, S., Baker, E., Holman, K., Lane, S. A., Nancarrow, J. K., Whitmore, S. A., Stallings, R. L., Hildebrand, C. E., Richards, R. I., Sutherland, G. R., Callen, D. F. A refined physical map of the long arm of human chromosome 16. Genomics 10: 308-312, 1991.<br /><br />2. De Marco Garcia, N. V., Karayannis, T., Fishell, G. Neuronal activity is required for the development of specific cortical inteeuron subtypes. Nature 472: 351-355, 2011.<br /><br />3. Parmentier, M., Passage, E., Vassart, G., Mattei, M.-G. The human calbindin D28k (CALB1) and calretinin (CALB2) genes are located at 8q21.3-q22.1 and 16q22-q23, respectively, suggesting a common duplication with the carbonic anhydrase isozyme loci. Cytogenet. Cell Genet. 57: 41-43, 1991.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002632-1	A04255	-	100 ug	$370		Add to Cart
BHA21002632-2	A04255-10ug	Sample	10 ug	$99		Add to Cart
BHA21002632-3	A04255-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002632-4	A04255-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002632-5	A04255-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002632-6	A04255-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002632-7	A04255-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002632-8	A04255-FITC	FITC	100 ug	$570		Add to Cart
BHA21002632-9	A04255-HRP	HRP	100 ug	$570		Add to Cart
BHA21002632-10	A04255-APC	APC	100 ug	$670		Add to Cart
BHA21002632-11	A04255-PE	PE	100 ug	$670		Add to Cart
BHA21002632-12	A04255-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002632-13	A04255-carrier-free	carrier-free	100 ug	$370		Add to Cart

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