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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Calbindin/CALB1 Antibody Picoband®

SKU : BHA21007505

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Mfr.No.	PB9045, PB9045-10ug, PB9045-Biotin, PB9045-Cy3, PB9045-Dylight488, PB9045-Dylight550, PB9045-Dylight594, PB9045-FITC, PB9045-HRP, PB9045-APC, PB9045-PE, PB9045-iFluor647, PB9045-carrier-free
Alternative Names	Calbindin
Background	Calbindin is a calcium-binding protein belonging to the troponin C superfamily. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Calbindin/CALB1 Antibody Picoband® catalog # PB9045. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Buffers cytosolic calcium. May stimulate a membrane Ca (2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
Host	Rabbit
Immunogen Region	E.coli-derived human Calbindin recombinant protein (Position: A2-E175). Human Calbindin shares 99% amino acid (aa) sequence identity with both mouse and rat Calbindin.
Isotype	Rabbit IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Calbindin;Calbindin D28;D-28K;Vitamin D-dependent calcium-binding protein, avian-type;CALB1;CAB27;
Tissue Specificity	Expressed in all cell types so far analyzed.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P05937
Gene Id	793
Gene Name	CALB1
Sequence	Belongs to the calbindin family.
Subcellular Location	Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain, is recruited to sites of the plasma membrane containing increased PI (3,4,5)P3 or PI (3,4)P2, cell membrane targeting is also facilitared by interaction with CLIP3.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat, By Heat

Reference	1. Parmentier M.; "The human calbindins: cDNA and gene cloning.";Adv. Exp. Med. Biol. 255:233-240(1989). 2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.;"The mouse calretinin gene promoter region: structural and functional components.";Brain Res. Mol. Brain Res. 49:175-187(1997). 3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.;"Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.";Biochemistry 30:656-662(1991).

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007505-1	PB9045	-	100 ug	$370		Add to Cart
BHA21007505-2	PB9045-10ug	Sample	10 ug	$99		Add to Cart
BHA21007505-3	PB9045-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007505-4	PB9045-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007505-5	PB9045-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007505-6	PB9045-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007505-7	PB9045-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007505-8	PB9045-FITC	FITC	100 ug	$570		Add to Cart
BHA21007505-9	PB9045-HRP	HRP	100 ug	$570		Add to Cart
BHA21007505-10	PB9045-APC	APC	100 ug	$670		Add to Cart
BHA21007505-11	PB9045-PE	PE	100 ug	$670		Add to Cart
BHA21007505-12	PB9045-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007505-13	PB9045-carrier-free	carrier-free	100 ug	$370		Add to Cart

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