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Home / Primary Antibodies / Polyclonal Antibodies

Anti-C-X-C motif chemokine 16 CXCL16 Antibody Picoband®

SKU : BHA21006808

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Mfr.No.	PA1460, PA1460-10ug, PA1460-Biotin, PA1460-Cy3, PA1460-Dylight488, PA1460-Dylight550, PA1460-Dylight594, PA1460-FITC, PA1460-HRP, PA1460-APC, PA1460-PE, PA1460-iFluor647, PA1460-carrier-free
Alternative Names	C-X-C motif chemokine 16
Background	CXCL16, Chemokine (C-X-C motif) ligand 16, is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids ), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. By somatic cell hybrid analysis, the CXCL16 gene is mapped to 17p13, a locus separate from all other known chemokines. Chemotaxis assays found that CXCL16 induced a strong chemotactic response in activated CD8 T cells. In addition, CXCL16 induced calcium mobilization.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-C-X-C motif chemokine 16 CXCL16 Antibody catalog # PA1460. Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathop
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of mouse CXCL16.
Isotype	Rabbit IgG
Molecular Weight	26-35 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	C-X-C motif chemokine 16;Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein;SR-PSOX;Small-inducible cytokine B16;Transmembrane chemokine CXCL16;Cxcl16;Srpsox;
Tissue Specificity	Widely expressed. Not detected in purified B- and T-cells. .
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q8BSU2
Gene Name	CXCL16
Sequence	Belongs to the SFTPA family.
Subcellular Location	Membrane ; Single-pass type I membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, By Heat <br>Weste blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Matloubian, M., David, A., Engel, S., Ryan, J. E., Cyster, J. G.A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.Nature Immun. 1: 298-304, 2000.<br /><br />2. Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., Yonehara, S.Molecular cloning of a novel scavenger receptor for oxidized low absorbance lipoprotein, SR-PSOX, on macrophages.J. Biol. Chem. 275: 40663-40666, 2000.<br /><br />3. Wilbanks, A., Zondlo, S. C., Murphy, K., Mak, S., Soler, D., Langdon, P., Andrew, D. P., Wu, L., Briskin, M.Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, CX3C chemokines.J. Immun. 166: 5145-5154, 2001.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006808-1	PA1460	-	100 ug	$370		Add to Cart
BHA21006808-2	PA1460-10ug	Sample	10 ug	$99		Add to Cart
BHA21006808-3	PA1460-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006808-4	PA1460-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006808-5	PA1460-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006808-6	PA1460-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006808-7	PA1460-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006808-8	PA1460-FITC	FITC	100 ug	$570		Add to Cart
BHA21006808-9	PA1460-HRP	HRP	100 ug	$570		Add to Cart
BHA21006808-10	PA1460-APC	APC	100 ug	$670		Add to Cart
BHA21006808-11	PA1460-PE	PE	100 ug	$670		Add to Cart
BHA21006808-12	PA1460-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006808-13	PA1460-carrier-free	carrier-free	100 ug	$370		Add to Cart

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